A novel method has been found to produce 2,2′-anhydro-1-(&bgr;-L-arabinofuranosyl)thymine as a novel useful intermediate compound. A novel method has been further found to produce thymidine from 2,2′-anhydro-1-(&bgr;-L-arabinofuranosyl)thymine. A novel method has been further found to L-2′-deoxyribose derivatives as a useful synthetic intermediate through L-2,2′-anhydro-5,6-dihydrocyclouridine derivative. According to these methods, synthesis of various L-nucleic acid derivatives, synthesis of which has been difficult till now.
已经发现了一种新的方法来生产2,2'-去氧-1-(&bgr;-L-阿拉伯
呋喃糖基)胸腺
嘧啶作为一种新的有用中间化合物。进一步发现了一种新的方法来从2,2'-去氧-1-(&bgr;-L-阿拉伯
呋喃糖基)胸腺
嘧啶中生产胸腺
嘧啶。另外,还发现了一种新的方法,通过
L-2,2'-去氧-5,6-二氢环尿
嘧啶衍
生物来生产
L-2'-脱氧
核糖衍
生物作为有用的合成中间体。根据这些方法,合成各种L-核酸衍
生物,这些衍
生物的合成迄今为止一直很困难。