申请人:KURARAY NORITAKE DENTAL INC.
公开号:US20170196778A1
公开(公告)日:2017-07-13
The present invention provides a dental adhesive exhibiting excellent initial bond strength and bond durability to both enamel and dentin. The present invention relates to a dental adhesive containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); and a water-soluble polymerizable monomer (c). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1):
where X is an optionally substituted, linear or branched C
1
to C
6
aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR
1
—, —CO—NR
1
—, —NR
1
—CO—, —CO—O—NR
1
—, —O—CO—NR
1
—, and —NR
1
—CO—NR
1
—, and R
1
is a hydrogen atom or an optionally substituted, linear or branched C
1
to C
6
aliphatic group.
本发明提供了一种牙科粘接剂,具有优异的初始粘接强度和对牙釉质和牙本质的粘接耐久性。本发明涉及一种含有以下成分的牙科粘接剂:不对称丙烯酰胺-甲基丙烯酸酯化合物(a);含酸基的(甲基)丙烯酸聚合单体(b);以及水溶性聚合单体(c)。不对称丙烯酰胺-甲基丙烯酸酯化合物(a)由下述一般式(1)表示:其中X是可选择取代的线性或支链状的C1到C6脂肪族基或可选择取代的芳香族基,所述脂肪族基可被来自由—O—、—S—、—CO—、—CO—O—、—O—CO—、—NR1—、—CO—NR1—、—NR1—CO—、—CO—O—NR1—、—O—CO—NR1—和—NR1—CO—NR1—组成的至少一个连接基中断,R1为氢原子或可选择取代的线性或支链状的C1到C6脂肪族基。