4,4'-<(3,6-Pyridazinediyl)bis(cyanomethyl)>bis(benzeneacetonitrile) | 134882-07-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 4,4'-<(3,6-Pyridazinediyl)bis(cyanomethyl)>bis(benzeneacetonitrile)
• 英文别名: 3,6-Pyridazinediacetonitrile, alpha,alpha'-bis[4-(cyanomethyl)phenyl]-；2-[6-[cyano-[4-(cyanomethyl)phenyl]methyl]pyridazin-3-yl]-2-[4-(cyanomethyl)phenyl]acetonitrile
• CAS: 134882-07-8
• 化学式: C₂₄H₁₆N₆
• 分子量: 388.431
• InChiKey: XOLAASIAEXAKQQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  121
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3,6-二氯哒嗪 、 1,4-苯二乙腈 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 以20%的产率得到4,4'-<(3,6-Pyridazinediyl)bis(cyanomethyl)>bis(benzeneacetonitrile)
  参考文献：
  名称：

  Pyridyl dicyanoquinodimethane acceptors for electroactive solids

  摘要：

  A new synthetic strategy for dicyanoquinodimethane electron acceptors is presented and used to synthesize six such compounds for the first time. The general sequence is substitution of alpha,alpha'-dicyanoxylene alpha anions with electrophiles followed by oxidative dehydrogenation. Unlike most previous examples, these quinodimethanes (QDs) are alpha substituted, rather than ring substituted; thus, the substituents increase the aspect ratio of the QDs and extend the pi-systems. All contain at least one pyridyl substituent at an alpha-position, and the set includes polar, cationic, and phosphonic acid derivatives. The particular compounds were chosen for incorporation into specific types of potentially electroactive solids, although, in principle, the syntheses could accommodate a wide variety of other functional groups. The neutral QD compounds display two reversible reductions, while the cations show single, partially reversible electrochemical transitions. Syn-anti isomerism was noted for several of the QDs, and proton NMR assignments obtained by 2D COSY methods are reported.

  DOI：

  10.1021/jo00018a021

文献信息

• Pyridyl dicyanoquinodimethane acceptors for electroactive solids
  作者：H. E. Katz、M. L. Schilling

  DOI：10.1021/jo00018a021

  日期：1991.8

  A new synthetic strategy for dicyanoquinodimethane electron acceptors is presented and used to synthesize six such compounds for the first time. The general sequence is substitution of alpha,alpha'-dicyanoxylene alpha anions with electrophiles followed by oxidative dehydrogenation. Unlike most previous examples, these quinodimethanes (QDs) are alpha substituted, rather than ring substituted; thus, the substituents increase the aspect ratio of the QDs and extend the pi-systems. All contain at least one pyridyl substituent at an alpha-position, and the set includes polar, cationic, and phosphonic acid derivatives. The particular compounds were chosen for incorporation into specific types of potentially electroactive solids, although, in principle, the syntheses could accommodate a wide variety of other functional groups. The neutral QD compounds display two reversible reductions, while the cations show single, partially reversible electrochemical transitions. Syn-anti isomerism was noted for several of the QDs, and proton NMR assignments obtained by 2D COSY methods are reported.