(E)-8-hydroxy-3,7-dimethyloct-6-enal | 98666-10-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (E)-8-hydroxy-3,7-dimethyloct-6-enal
• 英文别名: (E)-8-hydroxy-3,7-dimethyl-6-octenal；e-8-Hydroxy-3,7-dimethyloct-6-enal
• CAS: 98666-10-5
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: UKZUYKZFAACFKI-BJMVGYQFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (E)-8-hydroxy-3,7-dimethyloct-6-enal 在 2-碘酰基苯甲酸 作用下， 以 二甲基亚砜 为溶剂， 反应 1.5h， 生成 (E)-2,6-dimethyloct-2-enedial
  参考文献：
  名称：

  A Divergent Approach to the Diastereoselective Synthesis of Several Ant-Associated Iridoids

  摘要：

  The ant-associated iridoids nepetalactol, actinidine, dolichodial, isoiridomyrmecin, and dihydronepetalactone were prepared from citronellal using a divergent approach. Key features include a three-step synthesis of the Individual antipodes of actinidine by a novel tandem cycloaddition/pyridine formation and a facile diastereoselective synthesis of both enantiomers of dolichodial.

  DOI：

  10.1021/ol100077z
• 作为产物：
  描述：

  香茅醛 在 叔丁基过氧化氢 、 selenium(IV) oxide 、 水杨酸 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 35.0h， 以17%的产率得到(E)-2,6-dimethyloct-2-enedial
  参考文献：
  名称：

  A Divergent Approach to the Diastereoselective Synthesis of Several Ant-Associated Iridoids

  摘要：

  The ant-associated iridoids nepetalactol, actinidine, dolichodial, isoiridomyrmecin, and dihydronepetalactone were prepared from citronellal using a divergent approach. Key features include a three-step synthesis of the Individual antipodes of actinidine by a novel tandem cycloaddition/pyridine formation and a facile diastereoselective synthesis of both enantiomers of dolichodial.

  DOI：

  10.1021/ol100077z

文献信息

• US4510319A
  申请人：——

  公开号：US4510319A

  公开（公告）日：1985-04-09
• A Divergent Approach to the Diastereoselective Synthesis of Several Ant-Associated Iridoids
  作者：Joel S. Beckett、James D. Beckett、John E. Hofferberth

  DOI：10.1021/ol100077z

  日期：2010.4.2

  The ant-associated iridoids nepetalactol, actinidine, dolichodial, isoiridomyrmecin, and dihydronepetalactone were prepared from citronellal using a divergent approach. Key features include a three-step synthesis of the Individual antipodes of actinidine by a novel tandem cycloaddition/pyridine formation and a facile diastereoselective synthesis of both enantiomers of dolichodial.