2-[2-[2-[2-[2-(2-benzylsulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol | 194425-17-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-[2-[2-[2-(2-benzylsulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
• CAS: 194425-17-7
• 化学式: C₁₉H₃₂O₆S
• 分子量: 388.525
• InChiKey: URJKTESOUPCLAC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.0
• 重原子数：
  26.0
• 可旋转键数：
  19.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  66.38
• 氢给体数：
  1.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  2-[2-[2-[2-[2-(2-benzylsulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol 在 吡啶 、 sodium hydroxide 、 氯化亚砜 、 camphor-10-sulfonic acid 、 四丁基硫酸氢铵 、 一水合肼 、 三乙胺 作用下， 以 甲醇 、 乙醇 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 95.0h， 生成 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (1-phenyl-5,8,11,14,17,20,23,26,29,32,35-undecaoxa-2-thiaheptatriacontan-37-yl)carbamate
  参考文献：
  名称：

  The design and synthesis of simple molecular tethers for binding biomembranes to a gold surface

  摘要：

  Molecular tethers have been synthesised for fixing biomembranes to a gold surface. These are comprised of a thiol at one end to bind to the gold, a polyethylenoxy chain of defined length (two, six or twelve ethylenoxy units) in the middle and a cholesteryl residue at the other end to insert into the biomembrane. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00698-4
• 作为产物：
  描述：

  2-{2-[2-(2-{2-[2-(2-Benzylsulfanyl-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-tetrahydro-pyran 在 D(+)-10-樟脑磺酸 作用下， 以 甲醇 为溶剂， 生成 2-[2-[2-[2-[2-(2-benzylsulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  参考文献：
  名称：

  The design and synthesis of simple molecular tethers for binding biomembranes to a gold surface

  摘要：

  Molecular tethers have been synthesised for fixing biomembranes to a gold surface. These are comprised of a thiol at one end to bind to the gold, a polyethylenoxy chain of defined length (two, six or twelve ethylenoxy units) in the middle and a cholesteryl residue at the other end to insert into the biomembrane. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00698-4

文献信息

• The design and synthesis of simple molecular tethers for binding biomembranes to a gold surface
  作者：Neville Boden、Richard J. Bushby、Steven Clarkson、Stephen D. Evans、Peter F. Knowles、Andrew Marsh

  DOI：10.1016/s0040-4020(97)00698-4

  日期：1997.8

  Molecular tethers have been synthesised for fixing biomembranes to a gold surface. These are comprised of a thiol at one end to bind to the gold, a polyethylenoxy chain of defined length (two, six or twelve ethylenoxy units) in the middle and a cholesteryl residue at the other end to insert into the biomembrane. (C) 1997 Elsevier Science Ltd.