Methyl 2-(5-methyl-2-propan-2-ylcyclohexyl)oxyacetate | 43195-93-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Methyl 2-(5-methyl-2-propan-2-ylcyclohexyl)oxyacetate
• CAS: 43195-93-3
• 化学式: C₁₃H₂₄O₃
• 分子量: 228.332
• InChiKey: LLZGWCXWFQLBIC-UHFFFAOYSA-N

物化性质

• 沸点：
  301.4±15.0 °C(Predicted)
• 密度：
  0.96±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Methyl 2-(5-methyl-2-propan-2-ylcyclohexyl)oxyacetate 在 sodium hydroxide 、 盐酸羟胺 作用下， 生成 N-hydroxy-2-{[5-methyl-2-(1-methylethyl)cyclohexyl]oxy}-acetamide
  参考文献：
  名称：

  萜类化合物为药物。七。萜烯异羟肟酸。

  摘要：

  DOI：

  10.1021/jm00295a055

文献信息

• Catalysts based on Amino-Sulfide Ligands for Hydrogenation and Dehydrogenation Processes
  申请人：GOUSSEV Dmitri

  公开号：US20150202609A1

  公开（公告）日：2015-07-23

  The present application discloses novel amino-sulfide metal catalysts for organic chemical syntheses including hydrogenation (reduction) of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for a variety of chemicals.

  本申请公开了一种新型氨基硫醚金属催化剂，用于有机化学合成，包括不饱和化合物的氢化（还原）或底物的脱氢。氢化底物化合物的范围包括酯类、内酯、油脂，生成醇、二醇和三醇作为反应产物。本申请的催化剂可用于在无溶剂条件下催化氢化反应。本申请的催化剂还允许氢化在无添加碱的情况下进行，并且可以代替使用主族元素的氢化物的传统还原方法。此外，本申请的催化剂可以在均相和/或无受体条件下催化脱氢反应。因此，本文提供的催化剂可用于大幅降低各种化学品制造过程的成本并改善其环境性能。
• Catalysts based on amino-sulfide ligands for hydrogenation and dehydrogenation processes
  申请人：Goussev Dmitri

  公开号：US10112887B2

  公开（公告）日：2018-10-30

  The present application discloses novel amino-sulfide metal catalysts for organic chemical syntheses including hydrogenation (reduction) of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for a variety of chemicals.

  本申请公开了新型氨基硫化物金属催化剂，用于有机化学合成，包括不饱和化合物的氢化（还原）或底物的脱氢。氢化底物化合物的范围包括酯、内酯、油和脂肪，反应产物为醇、二醇和三醇。目前应用的催化剂可用于在无溶剂条件下催化加氢反应。本催化剂还可以在不添加碱的情况下进行氢化反应，并可用于替代使用主族元素氢化物的传统还原方法。此外，本申请的催化剂还能在均质和/或无受体条件下催化脱氢反应。因此，本申请提供的催化剂可大大降低各种化学品生产工艺的成本并改善其环境状况。
• CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES
  申请人：Goussev, Dmitri

  公开号：EP2892879A1

  公开（公告）日：2015-07-15
• [EN] CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES<br/>[FR] CATALYSEURS À BASE DE LIGANDS AMINO-SULFURES POUR DES PROCESSUS D'HYDROGÉNATION ET DE DÉSHYDROGÉNATION
  申请人：GOUSSEV DMITRI

  公开号：WO2014036650A1

  公开（公告）日：2014-03-13

  The present application discloses novel amino-sulfide metal catalysts for organic chemical syntheses including hydrogenation (reduction) of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for a variety of chemicals.
• Terpene compounds as drugs. VII. Terpenylhydroxamic acids
  作者：Silvano Casadio、Antonio Mantegani、Amedeo Omodei Sale、Germano Coppi

  DOI：10.1021/jm00295a055

  日期：1970.1