4-(4-ethaneylcyclohexyl)cyclohexanecarboxylic acid | 84976-67-0

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-(4-ethaneylcyclohexyl)cyclohexanecarboxylic acid
• 英文别名: 4-(4-ethylcyclohexyl)cyclohexanecarboxylic acid；4-ethylcyclohexyl-4-cyclohexylcarboxylic acid；4'-ethyl-bicyclohexyl-4-carboxylic acid；Trans-4'-ethyl-(1,1'-bicyclohexyl)-4-carboxylic acid；4-(4-ethylcyclohexyl)cyclohexane-1-carboxylic acid
• CAS: 84976-67-0
• 化学式: C₁₅H₂₆O₂
• 分子量: 238.37
• InChiKey: OQIHEFMTIUJJET-UHFFFAOYSA-N

物化性质

• 沸点：
  355.8±10.0 °C(Predicted)
• 密度：
  1.008±0.06 g/cm3(Predicted)
• 溶解度：
  溶于甲醇

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2916209090
• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H315,H319,H335

反应信息

• 作为反应物：
  描述：

  4-(4-ethaneylcyclohexyl)cyclohexanecarboxylic acid 生成 4-(4-ethylcyclohexyl)cyclohexanecarbonyl chloride
  参考文献：
  名称：

  SUGIMORI, SHIGERU;KOJIMA, TETSUHIKO

  摘要：

  DOI：

文献信息

• Photoredox/Cobalt Dual‐Catalyzed Decarboxylative Elimination of Carboxylic Acids: Development and Mechanistic Insight
  作者：Kaitie C. Cartwright、Ebbin Joseph、Chelsea G. Comadoll、Jon A. Tunge

  DOI：10.1002/chem.202001952

  日期：2020.9.25

  Recently, dual‐catalytic strategies towards the decarboxylative elimination of carboxylic acids have gained attention. Our lab previously reported a photoredox/cobaloxime dual catalytic method that allows the synthesis of enamides and enecarbamates directly from N‐acyl amino acids and avoids the use of any stoichiometric reagents. Further development, detailed herein, has improved upon this transformation's

  近来，用于羧酸脱羧消除的双重催化策略已引起关注。我们的实验室以前曾报道过光氧化还原/钴肟双催化方法，该方法可直接从N酰基氨基酸合成酰胺和烯甲酸酯，并避免使用任何化学计量试剂。本文详述的进一步开发改进了这种转化的用途，进一步的实验为反应机理提供了新的见解。这些新的发展和见识有望帮助扩大光氧化还原/钴双催化系统。
• Synthesis of Spirocycles via Ni‐Catalyzed Intramolecular Coupling of Thioesters and Olefins
  作者：Wenfei Liu、Wenhua Xu、Juanjuan Wang、Hong Lu、Peng‐Fei Xu、Hao Wei

  DOI：10.1002/chem.202100390

  日期：2021.5.17

  investigations are consistent with an oxidative addition/olefin insertion/reductive elimination mechanism. The incorporated methylene sulfide substituent can undergo a variety of further reactions to increase molecular diversity and complexity. These results demonstrate that thioester derivatives can be used as powerful building blocks for the assembly of complex scaffolds.

  已开发出镍催化的硫代酸酯与烯烃的分子内偶联，可有效合成螺环，螺环是天然产物中常见的一种特权支架。这种转化的特征是酰基和硫醇基团同时转移到烯烃上，同时抑制了脱羰基作用和β-氢消除。最初的机理研究与氧化加成/烯烃插入/还原消除机理一致。掺入的亚甲基硫取代基可进行多种进一步的反应以增加分子多样性和复杂性。这些结果表明，硫酯衍生物可以用作组装复杂支架的有力基础。
• NANOMATERIALS
  申请人：Guide Therapeutics, Inc.

  公开号：US20210169804A1

  公开（公告）日：2021-06-10

  Lipid nanoparticle compositions for delivery of nucleic acids are described. The lipid nanoparticle may contain a conformationally constrained ionizable lipid as part of the composition. These compositions may allow for delivery of cargo without the need for a targeting ligand.

  描述了用于传递核酸的脂质纳米粒子组合物。脂质纳米粒子可能包含作为组合物的一部分的构象受限的可离子化脂质。这些组合物可能允许传递货物而无需靶向配体。
• Polymerizable liquid crystal composition, optically anisotropic film, optical film, polarizing plate, image display device, and organic electroluminescent display device
  申请人：FUJIFILM Corporation

  公开号：US11332669B2

  公开（公告）日：2022-05-17

  A polymerizable liquid crystal composition capable of manufacturing an optically anisotropic film having excellent light fastness; and an optically anisotropic film, an optical film, a polarizing plate, an image display device, and an organic electroluminescent display device, each of which uses the polymerizable liquid crystal composition. The polymerizable liquid crystal composition of an embodiment of the present invention contains a polymerizable liquid crystal compound having reverse-wavelength dispersion properties and an ultraviolet absorber represented by Formula (1), in which a maximum absorption wavelength A of the polymerizable liquid crystal compound and a maximum absorption wavelength B of the ultraviolet absorber satisfy Formula (2), and a content of the ultraviolet absorber is 1% to 20% by mass with respect to a content of the polymerizable liquid crystal compound.

  一种可制备具有优异耐光性的光学各向异性薄膜的可聚合液晶组合物；以及使用该可聚合液晶组合物的光学各向异性薄膜、光学膜、偏振板、图像显示装置和有机电致发光显示装置。本发明实施例的可聚合液晶组合物包含具有反向波长分散性质的可聚合液晶化合物和由式（1）表示的紫外线吸收剂，其中可聚合液晶化合物的最大吸收波长A和紫外线吸收剂的最大吸收波长B满足式（2），且紫外线吸收剂的含量相对于可聚合液晶化合物的含量为1%至20%的质量百分比。
• POLYMERIZABLE COMPOSITION COMPRISING POLYMERIZABLE COMPOUNDS, FILM, AND HALF MIRROR FOR PROJECTED-IMAGE DISPLAY
  申请人：Fujifilm Corporation

  公开号：EP3199561A1

  公开（公告）日：2017-08-02

  The present invention provides a polymerizable composition having low birefringence which contains at least two types of polymerizable compounds represented by Formula (I): in the formula, A represents a phenylene or a trans-1,4-cyclohexylene, L represents -OC(=O)-, -OC(=O)O-, and the like, m represents 3 to 12, Sp1 and Sp2 represent an alkylene of which -CH2- may be substituted with -O- or the like, and the like, and Q1 and Q2 represent a polymerizable group, and the like, in which when a number obtained by dividing the number of trans-1,4-cyclohexylenes represented by A by m is set to mc, the polymerizable compounds include a polymerizable compound satisfying 0.5 < mc < 0.7 and a polymerizable compound satisfying 0.1 < mc < 0.3. A film such as a low birefringence phase difference film or a reflection film having high selectivity in a reflection wavelength range can be provided by using the polymerizable composition.

  本发明提供了一种具有低双折射的可聚合组合物，该组合物含有至少两种由式（I）表示的可聚合化合物： 式中，A 代表亚苯基或反式-1,4-环己烯，L 代表-OC(＝O)-、-OC(＝O)O-等，m 代表 3 至 12，Sp1 和 Sp2 代表其中-CH2-可被-O-等取代的亚烷基等、以及 Q1 和 Q2 代表可聚合基团等，其中，当将 A 所代表的反式-1,4-环己烯的数目除以 m 所得到的数字设为 mc 时，可聚合化合物包括满足 0.5 < mc < 0.7的可聚合化合物和满足0.1 < mc < 0.3的可聚合化合物。使用该可聚合组合物可以提供一种薄膜，例如低双折射相位差薄膜或在反射波长范围内具有高选择性的反射薄膜。