(7E)-9,10-seco-ergosta-4,7,10(19),22t-tetraen-3-one semicarbazone | 117472-30-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (7E)-9,10-seco-ergosta-4,7,10(19),22t-tetraen-3-one semicarbazone
• 英文别名: (7E)-9,10-seco-ergosta-4,7,10(19),22t-tetraen-3-one semicarbazone；(7E)-9,10-Seco-ergosta-4,7,10(19),22t-tetraen-3-on-semicarbazon；9.10-Seco-ergostatetraen-(4.7c.10(19).22t)-on-(3)-semicarbazon
• CAS: 117472-30-7
• 化学式: C₂₉H₄₅N₃O
• 分子量: 451.696
• InChiKey: HOPFYRGBNKDMSK-KLFPQWRZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  33.0
• 可旋转键数：
  7.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.66
• 拓扑面积：
  67.48
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (7E)-9,10-seco-ergosta-4,7,10(19),22t-tetraen-3-one semicarbazone 、 溶剂黄146 、 丙酮酸 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Drinking Behavior and Motivation for Treatment Among Alcohol-Dependent Liver Transplant Candidates

  摘要：

  Alcohol misuse is the second most common indication for liver transplantation in the United States. Our post-transplant alcoholism treatment trial suggested that current interventions might not he transferable to liver transplantees. We sought to identify differences between patients awaiting liver transplantation and alcoholics entering treatment without severe liver disease. Thirty transplant patients were compared to thirty naltrexone study patients on medical status, alcohol and drug use, alcohol craving, motivation for treatment, psychiatric symptoms, anti psychosocial problems. Lifetime alcohol consumption was greater for transplant patients compared to naltrexone patients. In contrast to the naltrexone group, transplant patients denied craving for alcohol and showed little motivation for alcoholism treatment. Groups did not differ on other psychosocial measures. Liver transplant patients differ from patients in alcoholism treatment trials on measures of alcohol consumption, alcohol craving and motivation for treatment. Alcoholism interventions should accommodate their medical condition and boost motivation for continued abstinence. (C) 2001 by The Haworth Press Inc. All rights reserved.

  DOI：

  10.1300/j069v20n02_09
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 生成 (7E)-9,10-seco-ergosta-4,7,10(19),22t-tetraen-3-one semicarbazone
  参考文献：
  名称：

  Windaus; Buchholz, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1938, vol. 256, p. 273,274

  摘要：

  DOI：