methyl (1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-6-(3-(3-(trifluoromethyl)phenyl)ureido)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate 在
potassium tert-butylate 作用下,
以
二甲基亚砜 为溶剂,
生成
(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-[[3-(trifluoromethyl)phenyl]carbamoylamino]-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid