methyl 1α-methoxy-2α-methyl-<1,1'-bicylopropyl>-2β-carboxylate | 126909-16-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: methyl 1α-methoxy-2α-methyl-<1,1'-bicylopropyl>-2β-carboxylate
• 英文别名: methyl (1S,2R)-2-cyclopropyl-2-methoxy-1-methylcyclopropane-1-carboxylate
• CAS: 126909-16-8
• 化学式: C₁₀H₁₆O₃
• 分子量: 184.235
• InChiKey: IYEYBNSZTAERLV-NXEZZACHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.36
• 重原子数：
  13.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  35.53
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  methyl 1α-methoxy-2α-methyl-<1,1'-bicylopropyl>-2β-carboxylate 生成 methyl 4-cyclopropyl-2-methyl-4-oxobutanoate
  参考文献：
  名称：

  HERNDON, JAMES W.;TUMER, SENIZ U., J. ORG. CHEM., 56,(1991) N, C. 286-294

  摘要：

  DOI：
• 作为产物：
  描述：

  (cyclopropylmethoxycarbene)pentacarbonylchromium(0) 、 甲基丙烯酸甲酯 、 四氢呋喃 生成 methyl 1α-methoxy-2α-methyl-<1,1'-bicylopropyl>-2β-carboxylate
  参考文献：
  名称：

  HERNDON, JAMES W.;TUMER, SENIZ U., J. ORG. CHEM., 56,(1991) N, C. 286-294

  摘要：

  DOI：

文献信息

• Reaction of cyclopropylcarbene-chromium complexes with alkenes; Synthesis of cyclopropylcyclopropanes
  作者：James W. Herndon、Seniz U. Tumer

  DOI：10.1016/s0040-4039(01)80504-9

  日期：1989.1

  We have examined the reaction of cyclopropylcarbene-chromium complexes with alkenes. The reaction leads to the formation of cyclopropylcyclopropane derivatives in good yield, accompanied by minor amounts of ring-opened products. Conjugated dienes and α,β-unsaturated esters and amides appear to be suitable substrates for the reaction.

  我们已经研究了环丙基碳烯-铬配合物与烯烃的反应。该反应导致以高收率形成环丙基环丙烷衍生物，并伴随有少量的开环产物。共轭二烯和α，β-不饱和酯和酰胺似乎是反应的合适底物。
• Synthesis of bicyclopropyl derivatives from the reaction of cyclopropylcarbene-chromium complexes with alkenes
  作者：James W. Herndon、Seniz U. Tumer

  DOI：10.1021/jo00001a055

  日期：1991.1

  The reaction of cyclopropylcarbene-chromium complexes with alkenes has been examined. The reaction leads to cyclopropylcyclopropane derivatives in good yield, accompanied by minor amounts of ring-opened products. Conjugated dienes and alpha,beta-unsaturated esters and amides appear to be suitable substrates for the reaction. The products of the reaction are donor-acceptor substituted cyclopropanes and are further susceptible to transformations typical of this class of compounds.