9,10-dimethoxy-8-propyl-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline | 61065-10-9

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 原小檗碱生物碱及其衍生物
• 英文名称: 9,10-dimethoxy-8-propyl-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline
• 英文别名: 9,10-dimethoxy-2,3-methylenedioxy-8-propyl-berbine；9,10-Dimethoxy-2,3-methylendioxy-8-propyl-berbin；9,10-Dimethoxy-8-propyl-2,3-methylendioxy-berbin
• CAS: 61065-10-9
• 化学式: C₂₃H₂₇NO₄
• 分子量: 381.472
• InChiKey: CMVXZRHSWWPSHT-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  9,10-dimethoxy-8-propyl-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline 在 氢氧化钾 作用下， 以 甲醇 为溶剂， 生成 7,8-dimethoxy-2-methyl-1-propyl-3-(6-vinyl-benzo[1,3]dioxol-5-yl)-1,2,3,4-tetrahydro-isoquinoline
  参考文献：
  名称：

  四氢小ber碱及其衍生物的中枢抑制作用。

  摘要：

  Tetrahydropalmatine is known to have potent sedative and hypnotic action and the depressant effect on the central nervous system of some compounds to realted berberine was tested. The levorotatory isomer of tetrahydroberberine had a stronger activity among the synthesized compounds.

  DOI：

  10.1248/cpb.24.1909