5-methyl-19-nor-5β-cholest-9(10)-en-3,6-dione | 17756-94-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 5-methyl-19-nor-5β-cholest-9(10)-en-3,6-dione
• 英文别名: 5-methyl-19-nor-5β-cholest-9(10)-ene-3,6-dione；5β-methyl-19-nor-5β-cholest-9(10)-en-3,6-dione；5β-Methyl-19-nor-cholest-9-en-3,6-dion；5-methyl-19-nor-5β-cholestene-(9)-dione-(3.6)；5-Methyl-19-nor-5β-cholesten-(9)-dion-(3.6)；(5R,8S,13R,14S,17R)-5,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,4,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,6-dione
• CAS: 17756-94-4
• 化学式: C₂₇H₄₂O₂
• 分子量: 398.629
• InChiKey: MOQUMIIUDJMILP-UCQHEYBLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.92
• 重原子数：
  29.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  34.14
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  5-methyl-19-nor-5β-cholest-9(10)-en-3,6-dione 在 间氯过氧苯甲酸 作用下， 以 乙醚 为溶剂， 生成 9,10-epoxy-5-methyl-19-nor-5β,9α,10α-cholestane-3,6-dione
  参考文献：
  名称：

  Szczepek, Wojciech J., Acta Chimica Hungarica, 1986, vol. 123, # 3-4, p. 77 - 82

  摘要：

  DOI：
• 作为产物：
  描述：

  5-methyl-19-nor-5β-cholest-9-ene-3β,6β-diol 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 5-methyl-19-nor-5β-cholest-9(10)-en-3,6-dione
  参考文献：
  名称：

  残留燃油燃烧产生的细颗粒物质的特征。

  摘要：

  在732千瓦的锅炉中对四种不同的残留燃油进行了燃烧实验。通过旋风分离器将空气中的PM排放物样品空气分离成标称直径小于和大于2.5微米的馏分。但是，通过计算机控制的扫描电子显微镜（CCSEM）检查了几个样品，发现PM2.5部分的一部分由碳质空心球和直径最大为10微米的囊泡颗粒组成。在S，V，Ni，Fe，Cu，Zn和As K边缘以及Pb L边缘获得X射线吸收精细结构（XAFS）光谱数据。对S光谱的X射线吸收近边缘结构（XANES）区域进行反卷积，可以确定S的主要分子形式是硫酸盐（占总S的26-84％）和噻吩（占总S的13-39％）。PM2.5样品中的硫酸盐含量大于PM2.5 +样品中的硫酸盐含量。无机硫化物和元素硫的含量较低。所有样品的Ni XANES光谱与NiSO4的光谱非常吻合，而大多数V光谱与硫酸氧钒（VO.SO4.xH2O）的光谱非常相似。研究的其他金属（例如，Fe，Cu，Zn和Pb）也主要以硫酸盐形式存在。砷以砷（As

  DOI：

  10.1080/10473289.2000.10464157

文献信息

• Reactions of epoxides—XXI
  作者：J.M. Coxon、M.P. Hartshorn、C.N. Muir

  DOI：10.1016/s0040-4020(01)82925-2

  日期：——

  3α-Hydroxy-5,6-epoxycholestanes gave 6-hydroxy-3α,10α-oxido-5β-methyl-19-nor compounds in addition to 6-ketones and backbone rearranged Δ13(17)-olefins on BF3-catalysed rearrangement. Similar treatment of 3α-acetoxy-5β,6β-epoxycholestane gave 5α-acetoxy-cholestane-3α,6β-diol.

  3α-羟基-5,6-环氧胆甾烷除了6-酮和在BF 3催化的骨架上重排的Δ13 （17）-烯烃外，还产生6-羟基-3α，10α-氧化-5β-甲基-19-nor化合物。。对3α-乙酰氧基-5β，6β-环氧胆甾烷进行类似处理，得到5α-乙酰氧基-胆甾烷-3α，6β-二醇。
• Baeyer-villiger oxidation of C19-nor Ketosteroids
  作者：Shafiullah、M.A. Ghaffari、Hasrat Ali

  DOI：10.1016/0040-4020(80)80122-0

  日期：1980.1

  The Baeyer-Villiger oxidation of 1 in chloroform with perbenzoic acid yielded 3,4, 5, 7 and 8. Similarly, the ketone 2 provided 9 and 10. The mechanism involved in the formation of abnormal Baeyer-Villiger products has been suggested.

  的拜尔-维利格氧化1在氯仿中与过苯甲酸，得到3，4，5，7和8。类似地，酮2提供9和10。已经提出了与异常拜耳-维利格产物形成有关的机制。
• 212. Steroids and related compounds. Part III. The constitution of Westphalen's diol
  作者：Vladimir A. Petrow

  DOI：10.1039/jr9390000998

  日期：——
• Long-Term Monitoring and Analysis of Hourly Solar UV Radiation in the 290-380 <i>nm</i> Range in the Middle Region of Saudi Arabia
  作者：A.M. Al-Dhafiri、M.S. Al-Ayed、M. Bin Mahfoodh

  DOI：10.1080/10473289.2000.10464148

  日期：2000.6

  The UV and global solar radiation on a horizontal surface at ground level in Riyadh City (latitude 24 degrees 34' N, longitude 46 degrees 43' E) have been measured and analyzed. Measurements of UV radiation (295-385 nm) were recorded every 10 min for five years (January 1983-December 1987). The maximum recorded hourly mean irradiance UV radiation was 28 W/m(2) and occurred in July, while the minimum was 14 W/m(2) in December. A steady monthly value of K-vh = (UV/H) was obtained and equaled 2.9%. A similar trend was found for the monthly variation of K-t = (H/H-o) and K-v = (UV/H-o) Maximum values of 90% and 2.6% were recorded in June for K-t and K-v, respectively, while minimum values of 35% and 1%, respectively, were obtained in December. A linear correlation was obtained between K-v and K-t. These findings were discussed and connected to the meteorological events. The results were compared with the regions of Kuwait, Bahrain, Dhahran, and Makkah.
• Szczepek, Wojciech J., Bulletin of the Polish Academy of Sciences: Chemistry, 1986, vol. 34, # 3-4, p. 89 - 107
  作者：Szczepek, Wojciech J.

  DOI：——

  日期：——