(2S,3R,4S,5R,6R)-3,4-Bis-benzyloxy-5-dodecyloxy-2-methoxy-6-(1-phenyl-ethoxymethyl)-tetrahydro-pyran | 142025-42-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4S,5R,6R)-3,4-Bis-benzyloxy-5-dodecyloxy-2-methoxy-6-(1-phenyl-ethoxymethyl)-tetrahydro-pyran
• CAS: 142025-42-1
• 化学式: C₄₁H₅₈O₆
• 分子量: 646.908
• InChiKey: ONZANIUSXJUOGA-HPQIQHGLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.61
• 重原子数：
  47.0
• 可旋转键数：
  23.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  55.38
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  (2S,3R,4S,5R,6R)-3,4-Bis-benzyloxy-5-dodecyloxy-2-methoxy-6-(1-phenyl-ethoxymethyl)-tetrahydro-pyran 在 palladium on activated charcoal 甲醇 、 三氟甲磺酸酐 、 氢气 、 sodium methylate 、 乙酸酐 作用下， 以 甲醇 为溶剂， 生成 (3R,4R,5S,6R)-5-Dodecyloxy-6-hydroxymethyl-tetrahydro-pyran-2,3,4-triol
  参考文献：
  名称：

  Amphiphilic and mesogenic carbohydrates - II. sysnthesis and Characterisation of mono-o-(n-alkyl)-d-glucose derivates

  摘要：

  The synthesis of various amphiphilic o-(n-alkyl)-D-glucopyranoses, having the long alkyl chain (C8H17 - C16H33) in 2-, 3-, 4- or 6-position are described. The investigations of the thermal behaviour of 6-o-(13a-e), 4-o-(14a-e), 3-o-(15a-e) and 2-o-(n-alkyl)-D-glucopyranoses (16a-e) and the corresponding methyl-alpha-D-glucosides 4a-e, 8a-e and 12a-e, respectively, are summarized in this paper.

  DOI：

  10.1016/s0040-4020(01)92248-3
• 作为产物：
  描述：

  溴代十二烷 、 methyl-6-O-(methylphenyl)methyl-2,3-di-O-benzyl-α-D-glucopyranoside 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 (2S,3R,4S,5R,6R)-3,4-Bis-benzyloxy-5-dodecyloxy-2-methoxy-6-(1-phenyl-ethoxymethyl)-tetrahydro-pyran
  参考文献：
  名称：

  Amphiphilic and mesogenic carbohydrates - II. sysnthesis and Characterisation of mono-o-(n-alkyl)-d-glucose derivates

  摘要：

  The synthesis of various amphiphilic o-(n-alkyl)-D-glucopyranoses, having the long alkyl chain (C8H17 - C16H33) in 2-, 3-, 4- or 6-position are described. The investigations of the thermal behaviour of 6-o-(13a-e), 4-o-(14a-e), 3-o-(15a-e) and 2-o-(n-alkyl)-D-glucopyranoses (16a-e) and the corresponding methyl-alpha-D-glucosides 4a-e, 8a-e and 12a-e, respectively, are summarized in this paper.

  DOI：

  10.1016/s0040-4020(01)92248-3