(2E)-N,N,3,7-tetramethylocta-2,6-dienamide | 767329-63-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (2E)-N,N,3,7-tetramethylocta-2,6-dienamide
• 英文别名: (E)-N,N,3,7-tetramethylocta-2,6-dienamide
• CAS: 767329-63-5
• 化学式: C₁₂H₂₁NO
• 分子量: 195.305
• InChiKey: UUKQMSUVUXFYFA-PKNBQFBNSA-N

物化性质

• 沸点：
  325.2±21.0 °C(Predicted)
• 密度：
  0.896±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (E)-3,7-二甲基-2,6-辛二烯酸 、 三乙胺 、 盐酸二甲胺 、 二苯基膦叠氮化物 在 水 、 乙酸乙酯 、 Sodium sulfate-III 、 乙酸酐 、 hexanes 作用下， 以 四氢呋喃 为溶剂， 反应 16.17h， 以(E)-N,N,3,7-tetramethylocta-2,6-dienamide (0.40 g, 70%) was obtained by flash column chromatography (50% acetyl acetate in hexanes)的产率得到(2E)-N,N,3,7-tetramethylocta-2,6-dienamide
  参考文献：
  名称：

  TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS

  摘要：

  本申请提供了公式(I)的萜烯类似物或其药学上可接受的异构体、盐或酯，以及用于治疗神经疾病，如一般疼痛和神经病性疼痛的方法和用途。这些萜烯类似物还可以用于治疗中枢神经系统和外周神经系统中的其他电障碍。同时提供了合成公式I的萜烯类似物的方法。

  公开号：

  US20130267571A1

文献信息

• Alkyldienamides exhibiting taste and sensory effect in flavor compositions
  申请人：——

  公开号：US20040202619A1

  公开（公告）日：2004-10-14

  Compounds suitable for use as flavoring agents are disclosed. The compounds are used as flavors since they possess umami characteristics or other desirable organoleptic properties. The disclosed compounds are defined by the structure set forth below: 1 where X is selected from the group consisting of H, methyl, ethyl, n-propyl, and isopropyl; Y is selected from the group consisting of methyl, ethyl, cyclopropyl, isopropyl, n-propyl, n-butyl, sec-butyl, isobutyl, 2-methylbutyl, allyl, cyclobutyl, 2 cyclopentyl, CH 2 CH(OH)CH 3 , CH(CH 3 )CH 2 OH, CH 2 C(CH 3 )OH, CH 2 CH 2 OH, CH 2 CO 2 CH 3 , geranyl, neryl; or X and Y together form the structures 3 R 3 is selected from the group consisting of methyl and H; R 4 is selected from the group consisting of methyl and H; R 5 is selected from the group consisting of methyl, phenyl, benzyl, ethyl, propyl, butyl, isopropyl, phenylethyl, 4

  适用于用作调味剂的化合物已被披露。这些化合物被用作香料，因为它们具有鲜味特性或其他理想的感官特性。所披露的化合物由以下结构定义：其中X选自H、甲基、乙基、正丙基和异丙基组成的群体；Y选自甲基、乙基、环丙基、异丙基、正丙基、正丁基、仲丁基、异丁基、2-甲基丁基、烯丙基、环丁基、环戊基、CH2CH(OH)CH3、CH( )CH2OH、CH2C( )OH、CH2CH2OH、CH2CO2 、蒈烯基、莰基；或X和Y一起形成以下结构：R3选自甲基和H组成的群体；R4选自甲基和H组成的群体；R5选自甲基、苯基、苄基、乙基、丙基、丁基、异丙基、苯乙基。
• ALKYLDIENAMIDES EXHIBITING TASTE AND SENSORY EFFECT IN FLAVOR COMPOSITIONS
  申请人：Dewis Mark L.

  公开号：US20090311402A1

  公开（公告）日：2009-12-17

  Alkyldienamides compounds suitable for use as flavoring agents are disclosed. The compounds are used as flavors since they possess umami characteristics or other desirable organoleptic properties. The disclosed compounds are defined by the structure set forth below: wherein R is ethyl or cyclopropyl; and wherein R′ is methyl or butyl, with the proviso that when R is ethyl, R′ is not methyl.

  本发明公开了适用于作为调味剂的烷基二烯酰胺化合物。这些化合物用作调味剂，因为它们具有鲜味特性或其他理想的感官特性。所公开的化合物由以下结构定义：其中R为乙基或环丙基；R'为甲基或丁基，但当R为乙基时，R'不为甲基。
• Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions
  申请人：International Flavors & Fragrances Inc.

  公开号：EP2348014A1

  公开（公告）日：2011-07-27

  The present invention is directed to novel compounds and a process for augmenting or imparting a flavor enhancement effect or modifying the perception of one or more of the five basic taste qualities sweet, sour, salt , bitter and umami, to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup comprising the step of adding to a foodstuff, chewing gum, medicinal product, toothpaste, alcoholic beverage, aqueous beverage, snack, sauce or soup a flavor enhancement or modification of basic taste quality augmenting, enhancing or imparting quantity and concentration of at least one N-substituted unsaturated alkyl amide defined according to the structures: and

  本发明涉及一种新型化合物和一种工艺，用于增强或赋予食品、口香糖、药用 产品、牙膏、酒精饮料、水性饮料、小吃、酱料或汤的风味增强效果或改变对甜、酸、 咸、苦和鲜味这五种基本味觉品质中的一种或多种味觉品质的感知、在食品、口香糖、药用产品、牙膏、酒精饮料、水性饮料、点心、酱汁或汤中加入至少一种根据结构定义的 N-取代不饱和烷基酰胺，以增加、提高或赋予其数量和浓度，从而增强或改变基本味觉品质： 和
• Saturated and unsaturated N-Alkamides exhibiting taste and flavor enhancement effect in flavor compositions
  申请人：International Flavors & Fragrances, Inc.

  公开号：EP1642886B1

  公开（公告）日：2016-11-16
• Unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions
  申请人：International Flavors & Fragrances Inc.

  公开号：EP2348014B1

  公开（公告）日：2017-05-10