bartogenic acid | 79355-89-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: bartogenic acid
• 英文别名: (2R,3R,4R,4Ar,6aR,6bS,8aR,12S,12aS,14aR,14bR)-2,3,12-trihydroxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4,8a-dicarboxylic acid
• CAS: 79355-89-8
• 化学式: C₃₀H₄₆O₇
• 分子量: 518.691
• InChiKey: BBJQJXRZAZWPBL-AOVBODNOSA-N

物化性质

• 熔点：
  315-316 °C
• 沸点：
  670.1±55.0 °C(Predicted)
• 密度：
  1.28±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  37
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  135
• 氢给体数：
  5
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  bartogenic acid 在 间氯过氧苯甲酸 作用下， 以 甲醇 、 乙醚 、 氯仿 为溶剂， 反应 49.0h， 生成 dimethyl-12,13-epoxybartogenate
  参考文献：
  名称：

  Rao, G. S. R. Subba; Prasanna, S.; Kumar, V. P. Sashi, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1986, vol. 25, p. 113 - 122

  摘要：

  DOI：
• 作为产物：
  描述：

  2α,3β,19α-trihydroxyolean-12-en-24,28-dioic acid 28-β-D glucopyranoside ester 在 sodium hydroxide 作用下， 反应 0.17h， 以20 mg的产率得到bartogenic acid
  参考文献：
  名称：

  来自壳斗科 (Cupuliferae)，第 19 版的成分：来自 Quercus robur var. Stenocarpa Beck 的三萜皂苷和酰基黄酮类化合物。

  摘要：

  来自 Quercus robur L. var. Stenocarpa Beck 的叶子。除了四种已知的糖苷外，还分离出一种新的三萜皂苷，并鉴定为 28-β-D-吡喃葡萄糖基酯的 2α、3β、19α-三羟基-12-齐墩果烯-24,28-二羧酸 (1)。

  DOI：

  10.1002/ardp.19943271008

文献信息

• ACCELERATOR FOR INITIAL INSULIN SECRETION
  申请人：Use-Techno Corporation

  公开号：EP1674089A1

  公开（公告）日：2006-06-28

  The present invention provides an early insulin secretion stimulator consisting of a triterpene represented by the following general formula (1) and/or a triterpene represented by the following general formula (2). [where R1 represents COOH, etc., R11 and R12 represent CH2OH, etc., X1 represents hydrogen or OH and X11, X12, X21 and X22 represent OH, etc.]

  本发明提供了一种早期胰岛素分泌刺激剂，由以下通式（1）代表的三萜和/或以下通式（2）代表的三萜组成。 [其中 R1 代表 COOH 等，R11 和 R12 代表 CH2OH 等，X1 代表氢或 OH，X11、X12、X21 和 X22 代表 OH 等。］
• Insulin secretion potentiator
  申请人：Matsuyama Futoshi

  公开号：US20050143464A1

  公开（公告）日：2005-06-30

  The present invention provides early insulin secretion stimulators consisting of triterpenes represented by the following general formula (1) and/or triterpenes represented by the following general formula (2). [where R 1 represents COOH, etc., R 11 and R 12 represent CH 2 OH, etc., X 1 represents hydrogen or OH and X 11 , X 12 , X 21 and X 22 represent OH, etc.]
• METHOD FOR IDENTIFYING THE OAK SPECIES OF AN OAK WOOD SAMPLE
  申请人：SEGUIN MOREAU & Cº

  公开号：US20160011166A1

  公开（公告）日：2016-01-14

  The invention concerns a method for identifying the oak species including the following steps of: Providing an oak wood sample; Preparing said sample; Performing at least one analysis on the wood sample so as: to identify: from one to three molecules belonging to a 1 st category of molecules defined by the derivatives of oleanane-type triterpenes which derive from an aglycone of empirical formula C 30 H 48 O 6 , from one to three molecules belonging to a 2 nd category of molecules defined by the derivatives of oleanane-type triterpenes which derive from an aglycone of empirical formula C 30 H 46 O 7 , as well as derivatives of oleanane-type triterpenes which derive from an aglycone of empirical formula C 30 H 46 O 8 , then to determine the concentration of the identified molecules; Determining a ratio R; Identifying the oak species.
• [EN] GLUCONEOGENESIS INHIBITING AGENT<br/>[FR] AGENTS D'INHIBITION DE LA GLUCONEOGENESE
  申请人：USE TECHNO CORP

  公开号：WO2006054370A1

  公开（公告）日：2006-05-26

  [EN] The present invention provides a gluconeogenesis inhibiting agent containing as an active ingredient corosolic acid, an analogous compound of corosolic acid, or a pharmaceutically acceptable salt thereof.
  [FR] La présente invention concerne un agent d'inhibition de la gluconéogenèse, contenant en tant qu'ingrédient actif de l'acide corosolique, un analogue de l'acide corosolique ou l'un de leurs sels pharmaceutiquement acceptables.