2-(3,5-diiodo-4-hydroxy-phenyl)-butyric acid | 99071-43-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-(3,5-diiodo-4-hydroxy-phenyl)-butyric acid
• 英文别名: 2-(3,5-Dijod-4-hydroxy-phenyl)-buttersaeure；2-(4-Hydroxy-3,5-diiodophenyl)butanoic acid
• CAS: 99071-43-9
• 化学式: C₁₀H₁₀I₂O₃
• 分子量: 431.997
• InChiKey: SBFJAUAPENWCMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 一氯化碘 、 溶剂黄146 作用下， 生成 2-(3,5-diiodo-4-hydroxy-phenyl)-butyric acid
  参考文献：
  名称：

  Redel et al., Bulletin de la Societe Chimique de France, 1954, p. 342,344

  摘要：

  DOI：

文献信息

• The role of gender and family support on dietary compliance in an African American adolescent hypertension prevention study
  作者：Dawn K. Wilson、Ginell Ampey-Thornhill

  DOI：10.1207/s15324796abm2301_9

  日期：2001.2

  Social support experiences vary markedly across gender groups, and little is known about the role of social support in promoting healthy dietary compliance in African American adolescents who are at increased risk for developing hypertension. This study examined the relation between gender dietary social support, and compliance to a low sodium diet. Casual blood pressures were also examined in relation to dietary compliance and gender One hundred eighty-four healthy African American adolescents (83 boys, 101 girls) participated in an intensive 5-day low sodium diet (50 mEq/24 hr) as part of a hypertension prevention program. Emotional dietary social support from family members and friends was measured at baseline. Compliance was defined as urinary sodium excretion of less than or equal to 50 mEq/24 hr at postsodium restriction. The results indicated a significant Gender x Compliance effect for positive family support (p < .05). Girls who were compliant reported higher levels of dietary support from family members (19.2 +/- 7.8) than boys who were compliant (16.9 +/- 7.0). In contrast, boys who were compliant reported lower levels of dietary support from family members (16.9 +/- 7.0) than boys who were not compliant (20.2 +/- 7.5). Systolic blood pressure showed a trend toward decreasing in compliant participants (104.4 +/- 8.4 vs. 101.7 +/- 8.0, mm Hg, p < .06), but the effect diminished when Quetelet Index (kg/m(2)) was controlled for in the analyses (p < .12). These results suggest that higher levels of emotional dietary support from family members are associated with better adherence to short-term sodium restriction for African American girls as compared to boys. Further research is needed to determine the long-term impact of social support on sodium restriction in adolescent populations.