(E)-3-Methyl-5-((1S,2R,4aS,8aR)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl)-pent-2-enoic acid methyl ester | 64395-79-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (E)-3-Methyl-5-((1S,2R,4aS,8aR)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl)-pent-2-enoic acid methyl ester
• CAS: 64395-79-5
• 化学式: C₂₁H₃₄O₂
• 分子量: 318.5
• InChiKey: ULUVTDOVIRYSSF-TURPSCJKSA-N

反应信息

• 作为反应物：
  描述：

  (E)-3-Methyl-5-((1S,2R,4aS,8aR)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl)-pent-2-enoic acid methyl ester 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 15-hydroxy-cis-ent-cleroda-3,13(E)-diene
  参考文献：
  名称：

  On the constituents of linaria japonica Miq. III. The structure of linarienone, a new cis-clerodane-type diterpene.

  摘要：

  A new diterpene named linarienone (2) was isolated from the ether-soluble portion of the fresh subterranean part of Linaria japonica MIQ. (Scrophulariaceae). Linarienone (2) is a monoacetyl-monoangeloyl derivative of a 5β-methyl-cis-clerodane-type diterpene and the stereostructure including the absolute configuration has been established as 2 on the basis of the chemical and physicochemical evidence and the unequivocal conversion starting from linarienone (2) and linaridial (1) leading to a common 5β-methyl-cis-clerodane-type hydrocarbon (18).

  DOI：

  10.1248/cpb.26.79
• 作为产物：
  描述：

  LJ ester aldehyd-tosylhydrazone 在 sodium methylate 、 sodium cyanoborohydride 作用下， 以 环丁砜 、 甲醇 、 N,N-二甲基甲酰胺 为溶剂， 生成 (E)-3-Methyl-5-((1S,2R,4aS,8aR)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl)-pent-2-enoic acid methyl ester
  参考文献：
  名称：

  On the constituents of linaria japonica Miq. III. The structure of linarienone, a new cis-clerodane-type diterpene.

  摘要：

  A new diterpene named linarienone (2) was isolated from the ether-soluble portion of the fresh subterranean part of Linaria japonica MIQ. (Scrophulariaceae). Linarienone (2) is a monoacetyl-monoangeloyl derivative of a 5β-methyl-cis-clerodane-type diterpene and the stereostructure including the absolute configuration has been established as 2 on the basis of the chemical and physicochemical evidence and the unequivocal conversion starting from linarienone (2) and linaridial (1) leading to a common 5β-methyl-cis-clerodane-type hydrocarbon (18).

  DOI：

  10.1248/cpb.26.79