| 145412-63-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• CAS: 145412-63-1
• 化学式: C₂₂H₃₃NO₂
• 分子量: 343.51
• InChiKey: QVOCRFHXGPXFNY-BCOSZGAKSA-N

反应信息

• 作为反应物：
  描述：

  在 sodium hydroxide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 生成 (1R,2S,3S,3'R,4S,8R,11R,13R)-10-ethyl-3',8-dimethyl-2'-oxospiro[10-azatetracyclo[6.3.2.04,11.04,13]tridecane-2,1'-cyclohexane]-3-carbaldehyde 、 (1R,2S,3R,3'R,4S,8R,11R,13R)-10-ethyl-3',8-dimethyl-2'-oxospiro[10-azatetracyclo[6.3.2.04,11.04,13]tridecane-2,1'-cyclohexane]-3-carbaldehyde
  参考文献：
  名称：

  Chemistry of Denudatine V. Rearrangement Reactions of Denudatine

  摘要：

  Treatment of denudatine 1 with 10% HCl solution at 30-50 degrees C leads to rearrangement to two pairs of epimers (5A) and (5B), (8A) and (8B) as well as 7 and 15. The rearrangement mechanisms are discussed. Conversion of 7-->5A/5B-->15 under acid catalysis can be realized. While the conversion of 15 to 5A/5B can be realized with NaOH-DMF at 120-126 degrees C. Structures for 5A/5B, 7, 8A/8B and 15 were established on the basis of chemical and spectral methods.

  DOI：

  10.3987/com-96-7644
• 作为产物：
  描述：

  在 盐酸 作用下， 反应 3.0h， 生成
  参考文献：
  名称：

  Chemistry of Denudatine V. Rearrangement Reactions of Denudatine

  摘要：

  Treatment of denudatine 1 with 10% HCl solution at 30-50 degrees C leads to rearrangement to two pairs of epimers (5A) and (5B), (8A) and (8B) as well as 7 and 15. The rearrangement mechanisms are discussed. Conversion of 7-->5A/5B-->15 under acid catalysis can be realized. While the conversion of 15 to 5A/5B can be realized with NaOH-DMF at 120-126 degrees C. Structures for 5A/5B, 7, 8A/8B and 15 were established on the basis of chemical and spectral methods.

  DOI：

  10.3987/com-96-7644