硬脂酰胺丙胺氧化物 | 25066-20-0

• 物质功能分类: 有机原料 - 氨基化合物 - 酰胺类化合物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 硬脂酰胺丙胺氧化物
• 英文名称: N,N-dimethyl-3-stearamidopropan-1-amine oxide
• 英文别名: Octadecanamide, N-[3-(dimethyloxidoamino)propyl]-；N,N-dimethyl-3-(octadecanoylamino)propan-1-amine oxide
• CAS: 25066-20-0
• 化学式: C₂₃H₄₈N₂O₂
• 分子量: 384.646
• InChiKey: ZHXQBNMVWBJMFB-UHFFFAOYSA-N

物化性质

• LogP：
  5.094 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  27
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  47.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-[3-(二甲基氨基)丙基]十八烷酰胺 在 双氧水 作用下， 以 乙醇 为溶剂， 反应 12.0h， 以97%的产率得到硬脂酰胺丙胺氧化物
  参考文献：
  名称：

  含氟醚链的氧化胺的表面性质

  摘要：

  持久性有机污染物（POP）包括长链含氟表面活性剂，例如全氟辛酸（PFOA）和全氟辛烷磺酸（PFOS）。为了找出替代的含氟表面活性剂，我们合成了八种带有氟醚链的氧化胺。对它们的表面性能进行了评估，并与全氟烷基和烃类似物进行了比较。具有氟醚链的八种胺氧化物在临界胶束浓度（γcmc）下的表面张力在15.5至23.0 mN / m的范围内，而γcmc四种氟醚氧化胺低于全氟辛基类似物（16.4 mN / m）低于17 mN / m，远低于全氟己基（20.5 mN / m）和碳氢化合物类似物（24.2和24.7 mN / m）。八个具有氟​​醚链的氧化胺的临界胶束浓度（cmc）为3至535×10 -4  mol / L。四种氟醚氧化胺的cmc为3至21×10 -4  mol / L（0.2至1.0 g / L）与全氟辛基（0.4 g / L）和碳氢化合物类似物（4和10×10 -4  mol / L）相当并且比全氟己基类似物（36

  DOI：

  10.1016/j.jfluchem.2021.109793

文献信息

• Low pH hair conditioner and neutralizer conditioning compositions containing amine oxides
  申请人：Revlon, Inc.

  公开号：EP0133905A2

  公开（公告）日：1985-03-13

  Disclosed herein are cationic hair conditioning compositions comprising an amine oxide; and, water and sufficient acid to provide a pH for said composition of about or below the isoelectric pH of hair protein and an amine oxide concentration from about 0.1% about 10% based on the total weight of said hair conditioning composition. Also disclosed are neutralizer conditioning compositions comprising in addition to the components of the cationic hair conditioning compositions, an oxidizing agent.

  本文公开了阳离子护发组合物，该组合物包含氧化胺；以及水和足够的酸，以使所述组合物的 pH 值约为或低于头发蛋白质的等电点 pH 值，以及基于所述护发组合物总重量的约 0.1% 约 10% 的氧化胺浓度。 还公开了中和剂护发组合物，除了阳离子护发组合物的成分外，还包括氧化剂。
• Low pH hair conditioner compositions containing amine oxides
  申请人：Revlon, Inc.

  公开号：EP0168719A2

  公开（公告）日：1986-01-22

  The present invention relates to a cationic hair conditioning composition comprising: (a) An amine oxide of the formula: wherein R1 and R2 are the same or different moieties and are selected from fewer (C1-C4) alkyl, alkoxy and hydroxy alkyl groups, and R3 is an alkyl group containing 8 to 22 carbon atoms; and (b) water sufficient acid to provide pH for said composition of from about 4.5 to about 2.4 or less and an amine oxide concentration from about 0.5% to about 10% based on the total weight of said hair conditioning composition.

  本发明涉及一种阳离子护发组合物，包括 (a) 式中的氧化胺： 其中 R1 和 R2 是相同或不同的分子，并且选自较少的 (C1-C4) 烷基、烷氧基和羟基烷基，R3 是含有 8 至 22 个碳原子的烷基；以及 (b) 足够酸性的水，为所述组合物提供约 4.5 至约 2.4 或更低的 pH 值，以及基于所述 头发护理组合物总重量的约 0.5%至约 10%的氧化胺浓度。
• POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION
  申请人：Dow Corning Toray Co., Ltd.

  公开号：EP2022812A1

  公开（公告）日：2009-02-11

  (Problem) To provide a novel polyether-modified organopolysiloxane and a novel diorganopolysiloxane-polyether block copolymer that are more resistant to oxidation than the heretofore existing polyoxyalkylene-modified organopolysiloxanes and that are thus more resistant to producing allergenically antigenic oxidation products during elapsed time in storage. Also, to provide methods of producing this novel polyether-modified organopolysiloxane and novel diorganopolysiloxane-polyether block copolymer. (Solution) Organopolysiloxane that is modified by silicon-bonded polyglycidyl ether or glycidyl ether/alkylene oxide copolymer; diorganopolysiloxane-polyglycidyl ether block copolymer; a method of producing the preceding by a hydrosilylation reaction between organohydrogenpolysiloxane and polyglycidyl ether having a terminal double bond or a glycidyl ether/alkylene oxide copolymer having a terminal double bond; and a cosmetic that contains this modified organopolysiloxane or diorganopolysiloxane-polyglycidyl ether block copolymer.

  问题 提供一种新型聚醚改性有机聚硅氧烷和一种新型二甘醇聚硅氧烷-聚醚嵌段共聚物，它们比现有的聚氧亚烷基改性有机聚硅氧烷更耐受氧化，因此在储存过程中更不易产生致敏抗原氧化产物。同时，提供生产这种新型聚醚改性有机聚硅氧烷和新型二异甘聚硅氧烷-聚醚嵌段共聚物的方法。 (解决方案） 由硅键聚缩水甘油醚或缩水甘油醚/环氧丙烷共聚物改性的有机聚硅氧烷；二甘醇聚硅氧烷-聚缩水甘油醚嵌段共聚物；一种通过有机氢聚硅氧烷和具有末端双键的聚缩水甘油醚或具有末端双键的缩水甘油醚/环氧烷共聚物之间的氢硅烷化反应生产前述物质的方法；以及一种含有这种改性有机聚硅氧烷或二甘聚硅氧烷-聚缩水甘油醚嵌段共聚物的化妆品。
• Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation
  申请人：Okawa Tadashi

  公开号：US20100036062A1

  公开（公告）日：2010-02-11

  (Problem) To provide a novel polyether-modified organopolysiloxane and a novel diorganopolysiloxane-polyether block copolymer that are more resistant to oxidation than the heretofore existing polyoxyalkylene-modified organopolysiloxanes and that are thus more resistant to producing allergenically antigenic oxidation products during elapsed time in storage. Also, to provide methods of producing this novel polyether-modified organopolysiloxane and novel diorganopolysiloxane-polyether block copolymer. (Solution) Organopolysiloxane that is modified by silicon-bonded polyglycidyl ether or glycidyl ether/alkylene oxide copolymer; diorganopolysiloxane-polyglycidyl ether block copolymer; a method of producing the preceding by a hydrosilylation reaction between organohydrogenpolysiloxane and polyglycidyl ether having a terminal double bond or a glycidyl ether/alkylene oxide copolymer having a terminal double bond; and a cosmetic that contains this modified organopolysiloxane or diorganopolysiloxane-polyglycidyl ether block copolymer.
• CLEANSING COMPOSITION WITH VISUAL PARTICLES
  申请人：The Dial Corporation

  公开号：US20170049668A1

  公开（公告）日：2017-02-23

  A composition and a consumer product are provided for cleansing the skin. The composition includes, in a cosmetically suitable carrier, at least one surfactant and at least one solid particle. The composition is dispensed as a foam. The consumer product includes a container and a cleansing composition. The cleansing composition includes a cosmetically suitable carrier, at least one surfactant, and at least one solid particle.