| 221312-09-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• CAS: 221312-09-0
• 化学式: C₅₇H₇₆BrNO₁₈
• 分子量: 1143.13
• InChiKey: OQLLJMAOJQJXAR-GDZVQOOPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.54
• 重原子数：
  77.0
• 可旋转键数：
  15.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  241.58
• 氢给体数：
  3.0
• 氢受体数：
  18.0

反应信息

• 作为反应物：
  描述：

  5-(氨基维生素)戊胺 、 在 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 生成
  参考文献：
  名称：

  Direct observation of binding between biotinylated okadaic acids and protein phosphatase 2A monitored by surface plasmon resonance

  摘要：

  Two biotin conjugates of okadaic acid were synthesized for evaluating their interactions with protein phosphatase 2A by surface plasmon resonance (SPR). C7-biotinylated okadaic acid revealed strong binding affinity to the enzyme, while C1-biotinylated derivative being devoid of affinity, implying that the C7-biotin conjugate is a useful tool for biochemical studies of protein phosphatase 2A. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02474-5
• 作为产物：
  描述：

  黑海棉酸钠盐 在 三乙胺 作用下， 以 丙酮 、 乙腈 为溶剂， 反应 8.0h， 生成
  参考文献：
  名称：

  Direct observation of binding between biotinylated okadaic acids and protein phosphatase 2A monitored by surface plasmon resonance

  摘要：

  Two biotin conjugates of okadaic acid were synthesized for evaluating their interactions with protein phosphatase 2A by surface plasmon resonance (SPR). C7-biotinylated okadaic acid revealed strong binding affinity to the enzyme, while C1-biotinylated derivative being devoid of affinity, implying that the C7-biotin conjugate is a useful tool for biochemical studies of protein phosphatase 2A. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02474-5