| 186596-42-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 186596-42-9
• 化学式: C₆₁H₄₉FO₁₇
• 分子量: 1073.05
• InChiKey: YEZPZIZXKLVORE-NUGVRMOZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.63
• 重原子数：
  79.0
• 可旋转键数：
  18.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  211.79
• 氢给体数：
  0.0
• 氢受体数：
  17.0

反应信息

• 作为反应物：
  描述：

  在 2,4,6-三甲基吡啶 、 sodium methylate 、 silver trifluoromethanesulfonate 、 tin(ll) chloride 作用下， 以 甲醇 、 1,2-二氯乙烷 为溶剂， 生成 (2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6R)-6-(4-Allyloxy-benzyloxy)-4,5-dihydroxy-2-hydroxymethyl-tetrahydro-pyran-3-yloxy]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol
  参考文献：
  名称：

  Solid phase synthesis of polylactosamine oligosaccharide

  摘要：

  Solid phase synthesis of polylactosamine oligosaccharide was performed starting from resin supported lactose 1a,b. Glycosylation of 1a with the lactosamine unit 6 followed by delevulinoylation afforded tetrasaccharides, which were further converted into hexa- and octasaccharide and was cleaved from resin by TrBF(4) in CH2Cl2 to afford 7. Ester linked Ib was converted in a similar manner into hexasaccharide that was liberated under basic conditions to give 8. Subsequent deprotection into 9 was performed in three steps. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0960-894x(96)00535-5
• 作为产物：
  描述：

  2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->4)-1,2,3,6-tetra-O-benzoyl-D-glucopyranose 在 2,2'-联吡啶 、 zinc(II) fluoride 、 氢溴酸 、 乙酸酐 、 溶剂黄146 作用下， 生成
  参考文献：
  名称：

  Solid phase synthesis of polylactosamine oligosaccharide

  摘要：

  Solid phase synthesis of polylactosamine oligosaccharide was performed starting from resin supported lactose 1a,b. Glycosylation of 1a with the lactosamine unit 6 followed by delevulinoylation afforded tetrasaccharides, which were further converted into hexa- and octasaccharide and was cleaved from resin by TrBF(4) in CH2Cl2 to afford 7. Ester linked Ib was converted in a similar manner into hexasaccharide that was liberated under basic conditions to give 8. Subsequent deprotection into 9 was performed in three steps. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0960-894x(96)00535-5