1-[2,4-Bis[[tert-butyl(dimethyl)silyl]oxy]-6-hydroxyphenyl]-2-hydroxyethanone | 950682-23-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-[2,4-Bis[[tert-butyl(dimethyl)silyl]oxy]-6-hydroxyphenyl]-2-hydroxyethanone
• CAS: 950682-23-2
• 化学式: C₂₀H₃₆O₅Si₂
• 分子量: 412.674
• InChiKey: WHJCVJCOHWVXJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.34
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-[2,4-Bis[[tert-butyl(dimethyl)silyl]oxy]-6-hydroxyphenyl]-2-hydroxyethanone 在 吡啶 、 4-二甲氨基吡啶 、 三氟甲磺酸三甲基硅酯 、 水 、 potassium carbonate 、 对甲苯磺酸 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of pelargonidin 3-O-6″-O-acetyl-β-d-glucopyranoside, an acylated anthocyanin, via the corresponding kaempferol glucoside

  摘要：

  The first total synthesis of pelargonidin 3-O-6 ''-O-acetyl-beta-D-glucopyranoside, an acylated anthocyanin of magenta-col-ored Verbena flowers, was successfully carried out. The key intermediate, protected kaemferol 3-O-glucoside, was constructed by the Baker-Venkataraman rearrangement from a glycosyloxyacetophenone followed by Zn-Hg reduction to the corresponding acylated anthocyanin. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.06.134
• 作为产物：
  描述：

  1,3,5-三(甲氧基甲氧基)苯 在 palladium dihydroxide 正丁基锂 、 N-甲基吲哚酮 、 四丙基高钌酸铵 、 四甲基乙二胺 、 Dowex 50W-X₈ 、 水 、 氢气 、 三乙胺 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 、 乙酸乙酯 为溶剂， 生成 1-[2,4-Bis[[tert-butyl(dimethyl)silyl]oxy]-6-hydroxyphenyl]-2-hydroxyethanone
  参考文献：
  名称：

  Synthesis of pelargonidin 3-O-6″-O-acetyl-β-d-glucopyranoside, an acylated anthocyanin, via the corresponding kaempferol glucoside

  摘要：

  The first total synthesis of pelargonidin 3-O-6 ''-O-acetyl-beta-D-glucopyranoside, an acylated anthocyanin of magenta-col-ored Verbena flowers, was successfully carried out. The key intermediate, protected kaemferol 3-O-glucoside, was constructed by the Baker-Venkataraman rearrangement from a glycosyloxyacetophenone followed by Zn-Hg reduction to the corresponding acylated anthocyanin. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.06.134

文献信息

• Synthesis of pelargonidin 3-O-6″-O-acetyl-β-d-glucopyranoside, an acylated anthocyanin, via the corresponding kaempferol glucoside
  作者：Kin-ichi Oyama、Satoshi Kawaguchi、Kumi Yoshida、Tadao Kondo

  DOI：10.1016/j.tetlet.2007.06.134

  日期：2007.8

  The first total synthesis of pelargonidin 3-O-6 ''-O-acetyl-beta-D-glucopyranoside, an acylated anthocyanin of magenta-col-ored Verbena flowers, was successfully carried out. The key intermediate, protected kaemferol 3-O-glucoside, was constructed by the Baker-Venkataraman rearrangement from a glycosyloxyacetophenone followed by Zn-Hg reduction to the corresponding acylated anthocyanin. (C) 2007 Elsevier Ltd. All rights reserved.