methyl 3,4,6-tri-O-methyl-α-D-galactopyranoside | 22323-62-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 3,4,6-tri-O-methyl-α-D-galactopyranoside
• 英文别名: (2S,3R,4R,5S,6R)-2,4,5-trimethoxy-6-(methoxymethyl)oxan-3-ol
• CAS: 22323-62-2
• 化学式: C₁₀H₂₀O₆
• 分子量: 236.265
• InChiKey: MJCQVUQCEVACLB-SPFKKGSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  66.38
• 氢给体数：
  1.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  methyl 3,4,6-tri-O-methyl-α-D-galactopyranoside 、 乙酸酐 在 吡啶 作用下， 以94%的产率得到Methyl 2-O-acetyl-3,4,6-tri-O-methyl-α-D-galactopyranoside
  参考文献：
  名称：

  Meta-chloroperbenzoic acid as a selective reagent for the removal of O-propenyl groups. Its use in the synthesis of some d-galactopyranoside and 4-deoxy-l-threo-4-hexenopyranoside derivatives

  摘要：

  DOI：

  10.1016/s0040-4020(01)87843-1
• 作为产物：
  描述：

  Methyl 2-O-allyl-3,4,6-tri-O-methyl-α-D-galactopyranoside 在 potassium tert-butylate 、 三乙胺 、 间氯过氧苯甲酸 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.33h， 生成 methyl 3,4,6-tri-O-methyl-α-D-galactopyranoside
  参考文献：
  名称：

  Meta-chloroperbenzoic acid as a selective reagent for the removal of O-propenyl groups. Its use in the synthesis of some d-galactopyranoside and 4-deoxy-l-threo-4-hexenopyranoside derivatives

  摘要：

  DOI：

  10.1016/s0040-4020(01)87843-1

文献信息

• Study on the constituents of Desmodium styracifolium.
  作者：Tomoko KUBO、Syuichi HAMADA、Toshihiro NOHARA、Zhi-rou WANG、Hideo HIRAYAMA、Keiichi IKEGAMI、Ken YASUKAWA、Michio TAKIDO

  DOI：10.1248/cpb.37.2229

  日期：——

  Two triterpenoid saponins (1 and 2) were isolated from Desmodii Herba [the dried whole plants of Desmodium styracifolium (Osbeck) Merr. (Leguminosae)] and their chemical structures were characterized as soyasaponin I and a new saponin, 3-O-[alpha-L-rhamnopyranosyl-(1----2)-beta-D-galactopyranosyl- (1----2)-beta-D-glucuronopyranosyl]soyasapogenol E, respectively, by chemical and spectroscopic means

  从Desmodii Herba [满地香（Desmodium styracifolium（Osbeck）Merr）干燥的整株植物中分离出了两个三萜皂苷（1和2）。（豆科）]及其化学结构被表征为大豆皂苷I和新的皂苷3-O- [α-L-鼠李糖基-（1 ---- 2）-β-D-吡喃半乳糖基-（1 ---- 2）通过化学和光谱方法分别测定β-D-D-葡萄糖醛酸吡喃糖基]大豆皂酚E。
• Determination of polysaccharide linkage and branching by reductive depolymerization. Gas-liquid chromatography and gas-liquid chromatography-mass spectrometry reference data
  作者：Agnes Van Langenhove、Vernon N. Reinhold

  DOI：10.1016/s0008-6215(00)90691-8

  日期：1985.11

  A series of partially methylated anhydro-D-alditol acetates has been prepared and analyzed by g.l.c. and g.l.c.-m.s. The reference compounds were obtained by reductive cleavage of permethylated and partially methylated standard methyl glycosides, and standard di-, tri-, and tetra-saccharides of known composition and linkage. Structural characterization included retention times on g.l.c. using DB-225

  制备了一系列部分甲基化的无水D-醛糖醇乙酸酯，并通过glc和glc-ms分析。参比化合物是通过还原裂解全甲基化和部分甲基化的标准甲基糖苷以及标准的二，三和四已知组成和连接的糖。结构表征包括使用DB-225毛细管色谱柱在glc上的保留时间以及在化学和电离模式下的质谱分析。这个编译的库允许进一步评估还原性切割程序用于确定新的和更复杂的寡糖的连接或分支（或两者）的适用性。该技术已应用于微克量的细菌膜寡糖和从甘露糖苷病患者的尿液中获得的糖类。
• Studies on the constituents of Pueraria lobata. IV. Chemical constituents in the flowers and the leaves.
  作者：JUN-EI KINJO、TAKASHI TAKESHITA、YOKO ABE、NAOKO TERADA、HIROSHI YAMASHITA、MASAKI YAMASAKI、KAZUO TAKEUCHI、KOTARO MURAKAMI、TOSHIAKI TOMIMATSU、TOSHIHIRO NOHARA

  DOI：10.1248/cpb.36.1174

  日期：——

  A new triterpenoidal saponin, 3-O-[α-L-rhamnopyanosyl(1→2)-α-L-arabinopyranosyl(1→2)-β-D-glucuronopyranosyl]sophoradio (I), was isolated from the flowers of Pueraria lobata (WILLD.) OHWI (Leguminosae). Its structure was elucidated on the basis of chemical and physicochemical evidence. In addition, a known oligoglycoside kaikasaponin III (II) was isolated from both flowers and leaves of this plant, together with several known aromatic compounds.

  从野葛（Pueraria lobata (WILLD.) OHWI）（豆科植物）的花中分离出一种新的三萜类皂甙--3-O-[α-L-rhamnopyanosyl(1→2)-α-L-arabinopyranosyl(1→2)-β-D-glucuronopyranosyl]sophoradio (I)。根据化学和物理化学证据阐明了其结构。此外，还从该植物的花和叶中分离出一种已知的低聚糖苷 kaikasaponin III (II)，以及几种已知的芳香族化合物。
• A convenient method for the preparation of all of the partially methylated derivatives of methyl α-d-mannopyranoside and α-d-galactopyranoside
  作者：Tomohiro Mega、Atsushi Nishikawa、Tokuji Ikenaka

  DOI：10.1016/0008-6215(83)88296-2

  日期：1983.2
• NAKANO, KIMIKO;YAMASAKI, TOKUSHI;IMAMURA, YUKIKO;MURAKAMI, KOTARO;TAKAISH+, PHYTOCHEMISTRY, 28,(1989) N, C. 1215-1217
  作者：NAKANO, KIMIKO、YAMASAKI, TOKUSHI、IMAMURA, YUKIKO、MURAKAMI, KOTARO、TAKAISH+

  DOI：——

  日期：——