N-[4,5-dihydroxy-6-(hydroxymethyl)-2-pentoxy-3-oxanyl]acetamide | 94483-64-4

• 物质功能分类: 生物化工 - 糖类化合物 - 单糖
• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[4,5-dihydroxy-6-(hydroxymethyl)-2-pentoxy-3-oxanyl]acetamide
• 英文别名: N-[4,5-dihydroxy-6-(hydroxymethyl)-2-pentoxyoxan-3-yl]acetamide
• CAS: 94483-64-4
• 化学式: C₁₃H₂₅NO₆
• 分子量: 291.34
• InChiKey: TXAKGSVWAUXDOK-UHFFFAOYSA-N

物化性质

• 沸点：
  538℃
• 密度：
  1.22
• 闪点：
  279℃

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  108
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• N-ACETYGLUCOSAMINE DERIVATIVES AND USE THEREOF
  申请人：MIURA Kyoko

  公开号：US20080293673A1

  公开（公告）日：2008-11-27

  The present invention relates to An N-acetylglucosamine derivative represented by the following formula (1), and a hyaluronic acid production promoting agent containing the same and a skin external preparation containing the same: wherein R 1 is a hydrogen atom or an alkyl group having 2 to 18 carbon atoms; R 2 , R 3 , and R 4 are hydrogen atoms or acyl groups having 2 to 18 carbon atoms and may be all the same or different from others; the steric structure at position 1 may be α or β; provided that R 1 , R 2 , R 3 , and R 4 must not be all hydrogen atoms. It is intended to provide an easily available hyaluronic acid production promoting agent and a skin external preparation whereby the production of hyaluronic acid can be promoted in the skin and thus the skin can be maintained in a vital and moist state so that it is expected that the human skin can be prevented from age.

  本发明涉及以下式（1）所表示的N-乙酰葡萄糖氨衍生物，以及含有该衍生物的透明质酸生产促进剂和皮肤外用制剂：其中，R1是氢原子或具有2至18个碳原子的烷基；R2、R3和R4是氢原子或具有2至18个碳原子的酰基，可以全部相同或不同；位置1的立体结构可以是α或β；前提是R1、R2、R3和R4不能全部是氢原子。旨在提供一种易于获得的透明质酸生产促进剂和皮肤外用制剂，通过促进皮肤中透明质酸的产生，从而使皮肤保持活力和湿润状态，预防人体皮肤老化。
• Nucleic acid conjugate
  申请人：Kyowa Kirin Co., Ltd.

  公开号：US10745700B2

  公开（公告）日：2020-08-18

  The present invention relates to a nucleic acid conjugate represented by the following formula 1: wherein X is an oligonucleotide, L1 and L2 are each independently sugar ligand, and S1, S2 and S3 are each independently a linker.

  本发明涉及下式 1 所代表的核酸共轭物： 其中 X 是寡核苷酸，L1 和 L2 各自独立地为糖配体，S1、S2 和 S3 各自独立地为连接体。
• NUCLEIC ACID CONJUGATE
  申请人：Kyowa Hakko Kirin Co., Ltd.

  公开号：US20190055558A1

  公开（公告）日：2019-02-21

  The present invention relates to a nucleic acid conjugate represented by the following formula 1: wherein X is an oligonucleotide, L1 and L2 are each independently sugar ligand, and S1, S2 and S3 are each independently a linker.
• US7393937B2
  申请人：——

  公开号：US7393937B2

  公开（公告）日：2008-07-01