2-acetylamino-α-D-2-deoxy-glucose | 72-87-7

• 物质功能分类: 生物化工 - 糖类化合物 - 单糖
• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-acetylamino-α-D-2-deoxy-glucose
• 英文别名: 2-acetylamino-α-D-2-deoxy-glucopyranose；N-Acetyl-D-glucosamin；N-[(2S,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
• CAS: 72-87-7；1136-42-1；1136-44-3；6082-29-7；6730-06-9；7772-94-3；10036-64-3；14131-60-3；14131-64-7；14131-68-1；14215-68-0；62057-49-2；62057-50-5；62057-51-6；62057-52-7；62057-53-8；62057-54-9；62057-55-0；62057-56-1；62075-50-7；62137-54-6；134451-97-1；134522-12-6；148347-16-4
• 化学式: C₈H₁₅NO₆
• 分子量: 221.21
• InChiKey: OVRNDRQMDRJTHS-IWBQZKFYSA-N

物化性质

• 熔点：
  211 °C
• 沸点：
  595.4±50.0 °C(Predicted)
• 密度：
  1.50
• LogP：
  -2.314 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  119
• 氢给体数：
  5
• 氢受体数：
  6

制备方法与用途

该化合物2-乙酰氨基-2-脱氧-α-D-吡喃葡萄糖主要用于科研。

文献信息

• USE OF SULPHATED GLYCOLIPIDS AS PROMOTERS OF NEURITIC GROWTH, MYELINATION AND INHIBITING THE PROLIFERATION OF ASTROGLIA AND MICROGLIA
  申请人：CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)

  公开号：US20150307539A1

  公开（公告）日：2015-10-29

  A compound having formula I, in which R 1 is an alkenyl group C 5 -C 25 containing one or more double carbon-carbon bonds, R 2 is selected independently from the group consisting of methyl and fluorinated methyl, and R 3 and/or R 4 is a SO 3 M group, in which M is selected from the group consisting of hydrogen, alkali metal, ammonium and quaternary amine, the other being hydrogen or acyl is provided. The compound can be used for the production of a drug for the treatment of central nervous system disorders selected from the group consisting of lesions caused by CNS trauma, demyelinating diseases, neuro-inflammatory diseases and mental disorders caused a low level of BDNF.