2,6-dibromo-3,5-dimethyl-1,4-benzoquinone | 87405-27-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,6-dibromo-3,5-dimethyl-1,4-benzoquinone
• 英文别名: 2,6-dibromo-3,5-dimethyl-[1,4]benzoquinone；2,6-Dibrom-3,5-dimethyl-[1,4]benzochinon；3.5-Dibrom-m-xylochinon；2,6-dibromo-3,5-dimethylcyclohexa-2,5-diene-1,4-dione
• CAS: 87405-27-4
• 化学式: C₈H₆Br₂O₂
• 分子量: 293.942
• InChiKey: LAGROTQXGYXIRW-UHFFFAOYSA-N

物化性质

• 熔点：
  176 °C
• 沸点：
  294.6±40.0 °C(Predicted)
• 密度：
  2.003±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,6-dibromo-3,5-dimethyl-1,4-benzoquinone 在 1,4-二氧六环 、 盐酸 、 丙酮 作用下， 生成 5,7-dibromo-6-hydroxy-8-methyl-2-oxo-2H-chromene-3-carboxylic acid
  参考文献：
  名称：

  The Reaction between Quinones and Metallic Enolates. XII. Dibromo-m-xyloquinone and Sodium Malonic Ester¹

  摘要：

  DOI：

  10.1021/ja01847a073
• 作为产物：
  描述：

  4-氯-3,5-二甲基苯酚 在 溴 、 硝酸 、 溶剂黄146 作用下， 生成 2,6-dibromo-3,5-dimethyl-1,4-benzoquinone
  参考文献：
  名称：

  52.卤化米-5-和米-2-二甲苯酚。混合氯溴衍生物

  摘要：

  DOI：

  10.1039/jr9480000209

文献信息

• CCXLVIII.—The direct formation of quinones from 2 : 6-disubstituted derivatives of 4-nitrophenol
  作者：Edward Charles Snell Jones、James Kenner

  DOI：10.1039/jr9310001842

  日期：——
• Analysis of aqueous humour proteins of eyes with and without pseudoexfoliation syndrome
  作者：Jens Berlau、Peter Lorenz、Ria Beck、Josef Makovitzky、Ursula Schlötzer-Schrehardt、Hans-Jürgen Thiesen、Rudolf Guthoff

  DOI：10.1007/s004170100357

  日期：2001.10

  Pseudoexfoliation syndrome (PEX) has been suggested to represent a blood-aqueous barrier impairment leading to a higher protein content in aqueous humour of eyes with PEX. However, the nature of a prospective PEX protein has not yet been described. We set out to reevaluate protein content and examine protein composition for prospective PEX protein candidates in aqueous humour of eyes with PEX syndrome. Aqueous humour of 52 patients with PEX and 38 without PEX signs was sampled during cataract or glaucoma surgery. Total aqueous protein concentration in the samples was analysed in 43 PEX specimens and 32 non-PEX specimens according to Bradford. Aqueous protein composition of all samples was determined by sodium dodecylsulphate polyacrylamide gel electrophoresis (SDS PAGE) and silver staining. Screening for amyloids was performed in nine PEX samples and six non-PEX samples by Congo Red staining and polarised light microscopy. Aqueous protein concentration was not significantly increased in PEX eyes in comparison with non-PEX eyes. Furthermore, we could not detect any characteristic difference in protein band sizes of the two groups after SDS PAGE. However, we were able to show the presence of amyloid exclusively in aqueous humour of PEX patients. Conclusion: our results do not confirm a generally higher protein concentration in pseudoexfoliation syndrome eyes. This does not necessarily contradict a blood-aqueous barrier impairment but illustrates the variance in protein concentration between and within the two groups. No characteristic protein band allocatable to pseudoexfoliation syndrome proteins could be detected in any of the samples. However, our findings support the theory that the pseudoexfoliation syndrome is associated with an amyloid of a serum protein.
• 89. Halogenation of m-5- and m-2-xylenols. Preparation and structure of certain polyhalogeno-m-5- and -m-2-xylenols
  作者：C. H. R. Elston、A. T. Peters、F. M. Rowe

  DOI：10.1039/jr9480000367

  日期：——
• Hartshorn, Michael P.; Martyn, Robert J.; Vaughan, John, Australian Journal of Chemistry, 1983, vol. 36, # 4, p. 839 - 842
  作者：Hartshorn, Michael P.、Martyn, Robert J.、Vaughan, John、Wright, Graeme J.

  DOI：——

  日期：——
• Regionalisation and sustainability in the field of industrial production
  作者：Sven Graehl、Wolf Fïchtner、Otto Rentz

  DOI：10.1080/13504500109470068

  日期：2001.6

  Regional business concepts are said to have huge potential to support sustainable development in industrialised countries (e.g. Stransfeld, 1999). However, whereas efforts have been made to implement regional concepts within agriculture and forestry, empirical findings show that regional concepts are only of minor importance to managers within industrial production (Rentz et al., 2000). Considering this situation, the aim of the present article is to explain why regional business concepts have rarely been implemented in the field of industrial production. Therefore, in the course of the present article, a raster for the identification of relevant barriers on a personal, enterprise, inter-firm and macro-economic level will be developed and applied. Subsequently, suggestions for a set of measures to overcome these barriers to regionalisation will be given. The results have been identified in the framework of a questionnaire to about 30 decision makers of industrial companies within research, a project promoted by the German Ministry of Education and Research.