| 33068-18-7

• 物质功能分类: 生物化工 - 糖类化合物 - 单糖
• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 33068-18-7
• 化学式: C6H13NaO9P
• 分子量: 283.13
• InChiKey: TZQUTLWZPHPOSF-MVNLRXSJSA-N

物化性质

• 溶解度：
  H2O：50 mg/mL，澄清，无色

计算性质

• 辛醇/水分配系数(LogP)：
  -3.64
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  9

安全信息

• WGK Germany：
  3

文献信息

• HYDROPHILIC NANOPARTICLES SURFACE-MODIFIED WITH MONOSACCHARIDE PHOSPHATE OR MONOSACCHARIDE PHOSPHATE DERIVATIVES, ITS COLLOIDAL SOLUTION AND USE THEREOF
  申请人：HANWHA CHEMICAL CORPORATION

  公开号：US20140161734A1

  公开（公告）日：2014-06-12

  Disclosed are a composition including hydrophilic nanoparticles that have a monosaccharide-phosphate or a derivative thereof adhered to the surface thereof, a colloidal solution of the composition dispersed in water, and a magnetic resonance imaging contrast agent including the colloidal solution. According to the present invention, nanoparticles having biocompatibility and excellent water-dispersibility can be prepared by modifying the surface of inorganic nanoparticles. The prepared nanoparticles may be effectively used in a variety of applications including, for example, in vivo imaging applications such as an MRI contrast agent, nano-electronic convergence technologies such as a quantum dot light emitting device, biomedical applications such as hyperthermia, or the like. Moreover, compared to existing nanoparticles dispersed by a dispersion stabilizer known in the art, excellent dispersion stability and a relatively small hydrodynamic diameter may be attained.

  本发明涉及一种包括亲水性纳米颗粒的组合物，其表面附着有单糖酸盐或其衍生物，以及该组合物在水中分散的胶体溶液和包括该胶体溶液的磁共振成像对比剂。根据本发明，通过修饰无机纳米颗粒的表面，可以制备具有生物相容性和优异的水分散性的纳米颗粒。所制备的纳米颗粒可在多种应用中有效使用，包括体内成像应用，如MRI对比剂，纳米电子融合技术，如量子点发光装置，生物医学应用，如超热疗等。此外，与现有的通过分散稳定剂分散的纳米颗粒相比，可以获得优异的分散稳定性和相对较小的流体动力学直径。
• Cyclodextrin for the treatment of lysosomal storage diseases
  申请人：The United States of America, as represented by the Secretary, Dept. of Health and Human Services

  公开号：US11020422B2

  公开（公告）日：2021-06-01

  The invention provides for methods of treating lysosomal storage disorders and/or reduction of non-cholesterol lipids, using cyclodextrin compounds, including in combination with other therapeutics, including vitamin E.

  本发明提供了使用环糊精化合物治疗溶酶体贮积症和/或降低非胆固醇脂质的方法，包括与维生素 E 等其他治疗药物联合使用。
• CYCLODEXTRIN FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES
  申请人：The U.S.A. as represented by the Secretary, Department of Health and Human Services

  公开号：EP2879714A1

  公开（公告）日：2015-06-10
• Composition for Promoting Differentiation or Proliferation of Human Adipose-Derived Stem Cell
  申请人：LG Household & Health Care Ltd.

  公开号：US20210315799A1

  公开（公告）日：2021-10-14

  Provided are a cosmetic composition, a food composition, a pharmaceutical composition, and an over-the-counter (OTC) composition for skin elasticity enhancement and skin wrinkle reduction, a composition for promoting differentiation or proliferation of human adipose-derived stem cells, and a method of enhancing skin elasticity including administering the compositions to an individual other than a human, each composition including at least one substance selected from the group consisting of formononetin, emodin, artepillin C, carnosic acid, palmitamide, sodium guaiazulene sulfonate, caffeic acid, acetyl mandelic acid, laccaic acid, ubiquinone, hydroxycinnamic acid, xanthophyll, raspberry ketone, gallic acid, terpineol, sodium mannose phosphate, tropolone, glycyrrhetinic acid, lanosterol, sodium riboflavin phosphate, menadione, thioctic acid, lactoflavin, onion extract, rice bran extract, bamboo extract, carrot extract, Hibiscus extract, Magnoliae cortex extract, Aloe vera extract, and fractions of the extracts as an active ingredient.
• US9457104B2
  申请人：——

  公开号：US9457104B2

  公开（公告）日：2016-10-04