Cyclohexanemethanol, 4-(1-methylethenyl)-, cis- | 22521-57-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Cyclohexanemethanol, 4-(1-methylethenyl)-, cis-
• 英文别名: cis-8-p-menthen-7-ol；cis-shisool；cis-4-Isopropenyl-cyclohexylmethanol
• CAS: 22521-57-9；123175-89-3
• 化学式: C₁₀H₁₈O
• 分子量: 154.252
• InChiKey: GMYHXOPIKMGWOM-AOOOYVTPSA-N

物化性质

• 沸点：
  227.0±9.0 °C(Predicted)
• 密度：
  0.904±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.36
• 重原子数：
  11.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  Cyclohexanemethanol, 4-(1-methylethenyl)-, cis- 在 palladium on activated charcoal 氢气 、 臭氧 作用下， 生成 cis-1-(4'-hydroxymethyl-cyclohexyl)ethanone
  参考文献：
  名称：

  嗅觉中的立体化学-活性关系。包含质子供体/质子受体单元的气味

  摘要：

  描述了新型的增香剂，其中该气味与两个官能团的相互作用有关，一个是H-供体（AH功能），另一个是H-受体（B功能）。通常，仅当两个结构元件（AH / B系统）之间的距离小于3Å时，才会产生气味。对-薄荷烷和铱烷系列的双功能衍生物用作推导该规则的模型。气味感知的立体特质是其建立的重要先决条件。

  DOI：

  10.1002/hlca.19800630109
• 作为产物：
  描述：

  紫苏子醇 在 manganese(IV) oxide 、 葡萄糖 、 fermenting Baker's Yeast 、 resin XAD 作用下， 以 水 为溶剂， 反应 101.0h， 生成 Cyclohexanemethanol, 4-(1-methylethenyl)-, cis-
  参考文献：
  名称：

  Stereochemical aspects of the bioreduction of the conjugated double bond of perillaldehyde

  摘要：

  A study on the regioselective reduction of the conjugate double bond of perillaldehyde is described. The chemical reduction of this substrate was investigated in order to provide a straightforward access to the relevant natural flavour, dihydroperill-aldehyde. The biological reduction of both natural (S)-(-)-perillaldehyde and synthetic (R)-(+)-perillaldehyde was accomplished by means of fermenting baker's yeast. The latter microorganism converted, with different diastereoselectivity, the (S)- and (R)-enantiomers into the corresponding trans and cis saturated alcohols, respectively. The origin of the hydrogen atoms added to the double bond was studied by deuterium labelling experiments and H-2 NMR measurements that clearly demonstrate a different mechanism of the biohydrogenation of the two enantiomeric forms of perillaldehyde. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2004.08.025

文献信息

• Loop-Grafted Old Yellow Enzymes in the Bienzymatic Cascade Reduction of Allylic Alcohols
  作者：Sabrina Reich、Bettina M. Nestl、Bernhard Hauer

  DOI：10.1002/cbic.201500604

  日期：2016.4.1

  Rational loop grafting transfers enzyme properties: The reaction activity in the bienzymatic cascade reduction of allylic alcohols was successfully transferred within ene reductases by the rational exchange of two β/α surface loop regions near the entrance of the active site.

  合理的环接枝转移酶特性：通过在活性位点入口附近的两个β/α表面环区域的合理交换，烯丙基醇的双酶级联还原反应活性成功地转移到烯还原酶中。
• Alicyclic compounds, their use and process for preparing same
  申请人：Firmenich S.A.

  公开号：US03993604A1

  公开（公告）日：1976-11-23

  Use of alicyclic compounds, some of which are new, as odor-modifying ingredients for manufacturing perfumes, perfumed products or synthetic essential oils, and as flavor-modifying ingredients for the manufacture of artificial flavors or for the aromatization of foodstuffs, animal feeds, pharmaceutical preparations or tobacco products. Process for preparing said alicyclic compounds.

  使用脂环化合物，其中一些是新的，作为制造香水、香料产品或合成精油的气味调节成分，以及作为制造人工香料或用于食品、动物饲料、制药制剂或烟草制品的香气化成分。制备该脂环化合物的过程。
• Composition for reducing malodors and method for using the same
  申请人：——

  公开号：US20030199402A1

  公开（公告）日：2003-10-23

  A composition for reducing malodors in the air and on inanimate surfaces comprises a combination of at least one malodor neutralizing agent, at least one malodor binding agent, at least one malodor masking agent, and at least one performance agent. In accordance with one embodiment of the invention, the composition includes a surfactant component, a water dispersible polymer component, a metallic salt, a fragrance component, and a liquid carrier.

  一种用于减少空气中和无生命表面恶臭的组合物由至少一种恶臭中和剂、至少一种恶臭结合剂、至少一种恶臭掩盖剂和至少一种性能剂组合而成。根据本发明的一个实施方案，组合物包括表面活性剂成分、水分散聚合物成分、金属盐、香料成分和液体载体。
• Padhi, Santosh Kumar; Bougioukou, Despina J.; Stewart, Jon D., Journal of the American Chemical Society, 2009, vol. 131, p. 3271 - 3280
  作者：Padhi, Santosh Kumar、Bougioukou, Despina J.、Stewart, Jon D.

  DOI：——

  日期：——
• Composition for reducing fabric wrinkles and method for using the same
  申请人：——

  公开号：US20040092423A1

  公开（公告）日：2004-05-13

  A composition for reducing fabric wrinkles is provided that generally comprises a silicone compound, a wetting agent, a drying agent, a liquid carrier, and a fragrance. The composition is preferably water clear, provides wrinkle reduction in a variety of fabrics, and is rapidly evaporated from the fabric. In accordance with one aspect of an exemplary embodiment of the invention, the wrinkle reducing composition does not employ a fragrance solubilizing agent.