2-(2-methyl-5-propan-2-ylphenoxy)-N-(3-nitrophenyl)acetamide | 1012417-36-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-(2-methyl-5-propan-2-ylphenoxy)-N-(3-nitrophenyl)acetamide
• CAS: 1012417-36-5
• 化学式: C₁₈H₂₀N₂O₄
• 分子量: 328.368
• InChiKey: RFFFUBMSQVFRGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  84.2
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  香芹酚 、 N-氯乙酰-3-硝基苯胺 在 sodium hydroxide 作用下， 以 丙酮 为溶剂， 反应 0.05h， 以90%的产率得到2-(2-methyl-5-propan-2-ylphenoxy)-N-(3-nitrophenyl)acetamide
  参考文献：
  名称：

  Synthesis and antibacterial activity of carvacryl ethers

  摘要：

  Structural modifications of phenolic monoterpenoid obtained by reacting carvacrol with various substituted -chloro acetanilides, to improve biological activities which give the product with better yield and higher purity under mild reaction conditions with the help of microwave irradiation techniques.

  DOI：

  10.1080/10286020903455907

文献信息

• Synthesis and antibacterial activity of carvacryl ethers
  作者：Jagdish U. Patil、Kamalakar C. Suryawanshi、Prakash B. Patil、Sanjay R. Chaudhary、Nilesh S. Pawar

  DOI：10.1080/10286020903455907

  日期：2010.2.1

  Structural modifications of phenolic monoterpenoid obtained by reacting carvacrol with various substituted -chloro acetanilides, to improve biological activities which give the product with better yield and higher purity under mild reaction conditions with the help of microwave irradiation techniques.