3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazine-1-yl)propoxy)quinolin-4-yl-oxy)aniline | 960299-67-6
中文名称
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中文别名
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英文名称
3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazine-1-yl)propoxy)quinolin-4-yl-oxy)aniline
英文别名
3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl-oxy)aniline；3-Fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)aniline；3-fluoro-4-[6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl]oxyaniline
CAS
960299-67-6
化学式
C24H29FN4O3
mdl
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分子量
440.518
InChiKey
ANMMNWBXWIPROY-UHFFFAOYSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
计算性质
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辛醇/水分配系数(LogP)：3.3
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重原子数：32
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可旋转键数：8
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环数：4.0
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sp3杂化的碳原子比例：0.38
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拓扑面积：73.1
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氢给体数：1
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氢受体数：8
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 4-(2-氟-4-硝基苯氧基)-6-甲氧基-7-(苄氧基)喹啉 7-benzyloxy-4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinoline 479690-03-4 C23H17FN2O5 420.397 —— 4-chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline 1061610-61-4 C18H24ClN3O2 349.86 —— 7-(3-chloropropoxy)-6-methoxy-4(1H)-quinolinone 1428788-16-2 C13H14ClNO3 267.712 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— 3-fluoro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292258-07-1 C30H32F2N4O5S 598.671 —— 2-fluoro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292258-17-3 C30H32F2N4O5S 598.671 —— N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)-2-methylbenzenesulfonamide 1292258-21-9 C31H35FN4O5S 594.707 —— 2,6-difluoro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1293291-28-7 C30H31F3N4O5S 616.661 —— 2-chloro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292258-23-1 C30H32ClFN4O5S 615.125 —— 2,4-difluoro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292257-90-9 C30H31F3N4O5S 616.661 —— 3-chloro-4-fluoro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292258-10-6 C30H31ClF2N4O5S 633.116 —— N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)-2-methoxybenzenesulfonamide 1292258-30-0 C31H35FN4O6S 610.707 —— 2,5-difluoro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292257-82-9 C30H31F3N4O5S 616.661 —— N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]-4-(3-thienyl)benzenesulfonamide 1558011-53-2 C34H35FN4O5S2 662.806 —— 2,6-dichloro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292258-27-5 C30H31Cl2FN4O5S 649.57 —— 2,5-dichloro-N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)benzenesulfonamide 1292258-01-5 C30H31Cl2FN4O5S 649.57 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-phenylpicolinamide 1491141-86-6 C36H36FN5O4 621.711 —— N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]-4-(1-methyl-1H-pyrazol-4-yl)benzenesulfonamide 1558011-52-1 C34H37FN6O5S 660.769 —— N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)-2-trifluoromethoxybenzenesulfonamide 1292258-15-1 C31H32F4N4O6S 664.678 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-fluorophenyl)picolinamide 1491141-89-9 C36H35F2N5O4 639.702 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-p-tolylpicolinamide 1491141-87-7 C37H38FN5O4 635.738 —— (E)-N-(3-fluoro-4-((6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)oxy)phenyl)-3-((2-methoxyphenyl)sulfonyl)acrylamide —— C34H37FN4O7S 664.755 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-methoxyphenyl)picolinamide 1491141-92-4 C37H38FN5O5 651.738 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-fluorophenyl)pyrimidine-2-carboxamide 1491142-32-5 C35H34F2N6O4 640.69 —— N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]-3-(3-thienyl)benzenesulfonamide 1558011-50-9 C34H35FN4O5S2 662.806 —— N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]-3-(3-furyl)benzenesulfonamide 1558011-49-6 C34H35FN4O6S 646.74 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-p-tolylpyrimidine-2-carboxamide 1491142-31-4 C36H37FN6O4 636.726 —— N-(3-fluoro-4-{6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yloxy}phenyl)-2-trifluoromethylbenzenesulfonamide 1292258-13-9 C31H32F4N4O5S 648.678 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(4-(trifluoromethyl)phenyl)picolinamide 1491141-91-3 C37H35F4N5O4 689.71 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-o-tolylpicolinamide 1491141-88-8 C37H38FN5O4 635.738 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(2-fluorophenyl)picolinamide 1491141-90-2 C36H35F2N5O4 639.702 —— N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]-3-(1-methyl-1H-pyrazol-4-yl)benzenesulfonamide 1558011-48-5 C34H37FN6O5S 660.769 —— 2-fluoro-N-[3-fluoro-4-({6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinolin-4-yl}oxy)phenyl]-5-(3-thienyl)benzenesulfonamide 1558011-51-0 C34H34F2N4O5S2 680.797 —— N-(3-fluoro-4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yloxy)phenyl)-4-(2,4-dimethoxyphenyl)picolinamide 1491141-93-5 C38H40FN5O6 681.764