DL-ornithine ; acetate | 60259-81-6

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: DL-ornithine ; acetate
• 英文别名: DL-Ornithin; Acetat；4-Methylsulfanyl-benzaldehydeoxime；acetic acid;2,5-diaminopentanoic acid
• CAS: 60259-81-6；92527-49-6
• 化学式: C₂H₄O₂*C₅H₁₂N₂O₂
• 分子量: 192.215
• InChiKey: PHEDTXJYYFZENX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.77
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  127
• 氢给体数：
  4
• 氢受体数：
  6

安全信息

• 海关编码：
  2922499990
• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

制备方法与用途

该产品主要用于抗菌治疗，适用于细菌和支原体感染。

文献信息

• Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
  申请人：——

  公开号：US20030040493A1

  公开（公告）日：2003-02-27

  The present invention provides two new classes of polyene macrolide amide derivatives useful for treating or preventing fungal infections. The new polyene macrolide amide derivatives exhibit antifungal activity and are more water-soluble than conventional polyene antibiotics, such as amphotericin B and amphotericin B methyl ester.

  本发明提供了两种新的聚烯烃大环内酰胺衍生物，可用于治疗或预防真菌感染。新的聚烯烃大环内酰胺衍生物表现出抗真菌活性，并且比传统的聚烯烃抗生素，如两性霉素B和两性霉素B甲酯，更具有水溶性。
• Amphotericin Derivatives
  申请人：Carreira Erick

  公开号：US20090186838A1

  公开（公告）日：2009-07-23

  The present invention provides new polyene macrolide derivatives which show very low toxicity while retaining high antifungal activity as compared with amphotericin B (AmB). These polyene macrolide derivatives comprise a polyene macrolide backbone having at least one free amino group, wherein the amino group is doubly alkylated with at least one hydrocarbon group carrying a total of at least two basic groups.

  本发明提供了新的多烯大环内酯衍生物，相比于两性霉素B（AmB），这些衍生物表现出非常低的毒性，同时保持高的抗真菌活性。这些多烯大环内酯衍生物包括至少具有一个自由氨基的多烯大环内酯骨架，其中该氨基被至少一个碳氢基团双烷基化，该碳氢基团携带至少两个碱性基团。
• Antimicrobial peptides and their use against plant pathogens
  申请人：ENICHEM S.p.A.

  公开号：EP0497366A2

  公开（公告）日：1992-08-05

  The present invention relates to several types of antimicrobial peptides including reverse antimicrobial peptides, antimicrobial oligopeptides and other antimicrobial compositions, such as cecropin P1. The present invention also relates to the use of these antimicrobial peptides to provide organisms, and, in particular, plants, with protection from microbial pathogens. Finally, the present invention relates to a screening method which may be useful for determining the phytotoxity of an antimicrobial peptide.

  本发明涉及几种类型的抗菌肽，包括反向抗菌肽、抗菌低聚肽和其他抗菌组合物，如雪腐镰刀菌素 P1。本发明还涉及使用这些抗菌肽来保护生物体，特别是植物免受微生物病原体的侵害。最后，本发明涉及一种筛选方法，该方法可用于确定抗菌肽的植物毒性。
• High internal aqueous phase water-in-oil type emulsion cosmetic composition
  申请人：SHISEIDO COMPANY LIMITED

  公开号：EP1064909A2

  公开（公告）日：2001-01-03

  A high internal aqueous phase water-in-oil type emulsion cosmetic composition comprising a cross-linkable polyether-modified silicone in an amount of 0.1 to 10.0% by weight and a water-soluble polymer having a weight average molecular weight of 2000 to 300,000, an inorganic salt and an amino acid salt or a polyether-modified silicone, and having a content of an aqueous phase component of at least 50% by weight.

  一种高内含水相油包水型乳液化妆品组合物，它包含一种可交联聚醚改性硅氧烷（重量百分比为 0.1 至 10.0%）和一种水溶性聚合物（重量平均分子量为 2000 至 300,000）、一种无机盐和一种氨基酸盐或一种聚醚改性硅氧烷，其水相组分的含量至少为 50%（重量百分比）。
• Water-in-oil emulsified cosmetic
  申请人：SHISEIDO COMPANY LIMITED

  公开号：EP1044672A1

  公开（公告）日：2000-10-18

  The present invention is a water-in-oil emulsified cosmetic comprising (A) a complex obtained by mixing an ampholytic surfactant or semi-polar surfactant and higher fatty acid, and (B) an inorganic salt and/or amino acid salt, in ortder to provide a water-in-oil emulsified cosmetic with excellent stability over time and superior usability which allows emulsification of a large amount of water in a wide range of oils from polar oil to non-polar oil.

  本发明是一种油包水型乳化化妆品，包括 (A) 两性表面活性剂或半极性表面活性剂与高级脂肪酸混合得到的复合物，和 (B) 无机盐和/或氨基酸盐，以提供一种油包水型乳化化妆品，该化妆品具有极佳的长期稳定性和卓越的可用性，可在从极性油到非极性油的各种油中乳化大量的水。