3'-O-(tert-butyldimethylsilyl)-4'-(hydroxymethyl)-thymidine | 139887-99-3
中文名称
——
中文别名
——
英文名称
3'-O-(tert-butyldimethylsilyl)-4'-(hydroxymethyl)-thymidine
英文别名
3'-O-t-butyldimethylsilyl4'-hydroxymethylthymidine；3'-O-t-butyldimethylsilyl-4'-c-hydroxymethylthymidine；1-[(2R,4S)-4-[tert-butyl(dimethyl)silyl]oxy-5,5-bis(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
CAS
139887-99-3
化学式
C17H30N2O6Si
mdl
——
分子量
386.521
InChiKey
FJHHUZIOCDGZAK-QWHCGFSZSA-N
BEILSTEIN
——
EINECS
——
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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密度：1.22±0.1 g/cm3(Predicted)
计算性质
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辛醇/水分配系数(LogP)：0.88
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重原子数：26
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可旋转键数：6
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环数：2.0
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sp3杂化的碳原子比例：0.76
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拓扑面积：108
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氢给体数：3
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氢受体数：6
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 3'-O-(叔丁基二甲基硅烷基)胸苷 3'-O-(t-butyldimethylsilyl)thymidine 40733-27-5 C16H28N2O5Si 356.494 3,5-双-o-(t-丁基二甲基甲硅烷基)胸腺嘧啶脱氧核苷 3',5'-O-di(tert-butyldimethylsilyl)thymidine 40733-26-4 C22H42N2O5Si2 470.757 —— 3'-tert-butyldimethylsilylthymidine 5'-carboxaldehyde 131118-61-1 C16H26N2O5Si 354.478 beta-胸苷 thymidine 146183-25-7 C10H14N2O5 242.232 —— 5'-O-(4,4'-dimethoxytrityl)-3'-O-(t-butyldimethylsilyl)-2'-deoxythymidine 80971-33-1 C37H46N2O7Si 658.867 保护胸苷 5'-O-(4-4'-dimethoxytrityl)thymidine 40615-39-2 C31H32N2O7 544.604 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 179178-45-1 C23H44N2O6Si2 500.783 —— (2R,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carbaldehyde 139888-01-0 C17H28N2O6Si 384.505 —— 3'-O-t-butyldimethylsilyl-4'-hydroxyiminomethylthymidine 139888-03-2 C17H29N3O6Si 399.519 —— 5'-O-[(trifluoromethyl)sulfonyl]-4'-C-[(trifluoromethylsulfonyl)-oxymethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-thymidine 879015-07-3 C19H28F6N2O10S2Si 650.647 —— 4'-C-[(thymin-1-yl)methyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-thymidine 879015-15-3 C22H34N4O7Si 494.62 —— 5'-O-benzoyl-3'-O-tert-butyldimethylsilyl-4'-(hydroxymethyl)thymidine 201684-53-9 C24H34N2O7Si 490.629 —— 4'-C-methylthymidine 139925-84-1 C11H16N2O5 256.258 —— 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(diphenyl)silyl]oxymethyl]-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 162052-67-7 C33H48N2O6Si2 624.925 —— 1-[(1S,3R)-1-hydroxy-8,8-dimethyl-4,7,9-trioxaspiro[4.5]decan-3-yl]-5-methyl-pyrimidine-2,4-dione 139925-86-3 C14H20N2O6 312.323 —— 1-[(1R,3R)-1-hydroxy-8,8-dimethyl-4,7,9-trioxaspiro[4.5]decan-3-yl]-5-methyl-pyrimidine-2,4-dione 140145-79-5 C14H20N2O6 312.323 —— 4'-Cyanothymidine 139888-11-2 C11H13N3O5 267.241 —— Thymidine-4'-C-carboxylic acid 194652-87-4 C11H14N2O7 286.241 —— (2R,3S,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(tert-butyl-dimethyl-silanyloxy)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-carbaldehyde 172280-71-6 C38H46N2O8Si 686.877 —— 4'-C-[(thymin-1-yl)methyl]-thymidine 879015-16-4 C16H20N4O7 380.357 —— 3'-O-tert-Butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-formyl-thymidin 162052-68-8 C33H46N2O6Si2 622.909 —— 4'-C-[(adenin-9-yl)methyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-thymidine 879015-09-5 C22H33N7O5Si 503.633 —— 1-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-5-((E)-7-hydroxy-hept-1-enyl)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 172280-73-8 C44H58N2O8Si 771.039 —— 3',5'-O-di[(1,1-dimethylethyl)dimethylsilyl]-4'-C-[(adenin-9-yl)-methyl]-thymidine 879015-10-8 C28H47N7O5Si2 617.896 —— N-{(E)-7-[(2R,3S,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(tert-butyl-dimethyl-silanyloxy)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-yl]-hept-6-enyl}-2,2,2-trifluoro-acetamide 172280-76-1 C46H58F3N3O8Si 866.063 —— 1-[(1R,10R,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-5-oxo-8,13-dioxa-2,6-diaza-tricyclo[8.2.1.02,7]trideca-3,6-dien-10-ylmethyl]-5-methyl-1H-pyrimidine-2,4-dione 1053655-43-8 C22H32N4O6Si 476.605 —— 3',5'-O-di[(1,1-dimethylethyl)dimethylsilyl]-4'-C-[(N6-benzoyladenin-9-yl)-methyl]-thymidine 879015-11-9 C35H51N7O6Si2 722.004 —— 5'-O-(mono-4-methoxytrityl)-4'-C-[(thymin-1-yl)methyl]-thymidine 879015-17-5 C36H36N4O8 652.704 —— N-{(E)-7-[(2R,3S,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-yl]-hept-6-enyl}-2,2,2-trifluoro-acetamide 172280-78-3 C40H44F3N3O8 751.8 —— N-(2-Hydroxymethyl)-3',5'-di-O-benzoylthymidine-4'-carboxamide 194652-97-6 C27H27N3O9 537.526 —— N-[(Aminocarbonyl)methyl]-3',5'-di-O-benzoylthymidine-4'-carboxamide 194652-93-2 C27H26N4O9 550.525 —— N,N-Dimethyl-3',5'-di-O-benzoylthymidine-4'-carboxamide 194652-95-4 C27H27N3O8 521.527 —— 4'-C-[(N6-benzoyladenin-9-yl)-methyl]-thymidine 879015-12-0 C23H23N7O6 493.479 —— 4'-C-[(adenin-9-yl)methyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-O2,5'-anhydrothymidine 879015-08-4 C22H31N7O4Si 485.618 —— 1-(2,3-dideoxy-4-C-hydroxymethyl-α-L-glycero-pent-2-enofuranosyl)thymine 139926-01-5 C11H14N2O5 254.243 —— 1-<(6R)-2,2-dimethyl-1,3,5-trioxaspiro<3.4>oct-7-en-6-yl>thymine 139926-00-4