β-D-galactofuranosyl-(1-1)-β-D-galactofuranoside | 124752-66-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: β-D-galactofuranosyl-(1-1)-β-D-galactofuranoside
• 英文别名: Galf(b1-1b)Galf；(2S,3R,4R,5S)-2-[(1R)-1,2-dihydroxyethyl]-5-[(2S,3R,4R,5S)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]oxyoxolane-3,4-diol
• CAS: 124752-66-5
• 化学式: C₁₂H₂₂O₁₁
• 分子量: 342.3
• InChiKey: WWLYXLBMFCCZBG-IIJVXAHISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  190
• 氢给体数：
  8
• 氢受体数：
  11

反应信息

• 作为产物：
  描述：

  methyl 6-O-benzyl-β-D-galactofuranoside 在 palladium on activated charcoal 吡啶 、 三氟甲磺酸三甲基硅酯 、 4 A molecular sieve 、 硫酸 、 氢溴酸 、 氢气 、 sodium methylate 、 乙酸酐 、 potassium carbonate 作用下， 以 甲醇 、 二氯甲烷 、 溶剂黄146 为溶剂， 反应 13.33h， 生成 β-D-galactofuranosyl-(1-1)-β-D-galactofuranoside
  参考文献：
  名称：

  Synthesis of some galactofuranosyl disaccharides using a galactofuranosyl trichloroacetimidate as donor

  摘要：

  2,3,5-Tri-O-benzoyl-6-O-benzyl-beta-D-galactofuranosyl trichloroacetimidate has been prepared for the first time and utilised as glycosyl donor for the synthesis of several disaccharides containing the beta-linked galactofuranoside moiety. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(98)00062-7

文献信息

• Synthesis of galactofuranose disaccharides of biological significance
  作者：Carla Marino、Oscar Varela、Rosa M. de Lederkremer

  DOI：10.1016/0008-6215(89)84147-3

  日期：1989.7

  disaccharide derivative having both units in the furanoid form. Thus, diisoamylborane reduction of the lactone function of 6 led to the disaccharide derivative 10, from which the methyl glycoside 12 was prepared. O-Debenzoylation of 12 gave the corresponding methyl beta-D-galactofuranosyl-(1----6)-beta-D-galactofuranoside. The free disaccharide beta-D-Galf-(1----6)-D-Galp and its acetylated derivative were

  通过氯化锡（IV）催化五-O-苯甲酰基-α，β-D-半乳糖呋喃糖的糖基化，然后用甲醇钠进行脱苯甲酰化，可以轻松获得甲基β-D-半乳糖呋喃糖苷。将1，与2,3,5-三-O-苯甲酰基-D-半乳糖基-1,4-内酯或与6-O-三苯甲基-内酯衍生物5进行糖基化，得到苯甲酰化的β-D-D-半呋喃糖基-（1- --6）-D-半乳糖-1,4-内酯6，收率极高。通过硼氢化物还原成糖基-糖醇7证实了二糖6的结构。1与4或5的缩合反应的副产物被鉴定为苯甲酰化的（1-1）-β，β'-D-半乳糖呋喃糖基二糖8。在氯化锡的存在下，通过向1中加水可容易地制备化合物8（收率88％）。8的O-脱苯甲酰化得到结晶的β' -D-半呋喃糖基-（1 ---- 1）-β-D-半呋喃糖苷 糖基内酯6构成用于合成具有两个呋喃形式的二糖衍生物的关键中间体。因此，内酯官能团的二异戊基硼烷还原导致二糖衍生物10，由此制备了甲基糖苷12。12的
• MARINO, CARLA;VARELA, OSCAR;LEDERKREMER, ROSA M. DE, CARBOHYDR. RES., 190,(1989) N, C. 65-76
  作者：MARINO, CARLA、VARELA, OSCAR、LEDERKREMER, ROSA M. DE

  DOI：——

  日期：——
• NUTRACEUTICAL COMPOSITIONS FROM MICROALGAE AND RELATED METHODS OF PRODUCTION AND ADMINISTRATION
  申请人：Solazyme, Inc.

  公开号：EP1993565A2

  公开（公告）日：2008-11-26
• [EN] NUTRACEUTICAL COMPOSITIONS FROM MICROALGAE AND RELATED METHODS OF PRODUCTION AND ADMINISTRATION<br/>[FR] COMPOSITIONS NEUTRACEUTIQUES DE MICROALGUES ET MÉTHODES ASSOCIÉES DE PRODUCTION ET ADMINISTRATION
  申请人：SOLAZYME INC

  公开号：WO2007136428A2

  公开（公告）日：2007-11-29

  (EN) Provided herein are polysaccharide compositions and methods of culturing microalgae to produce polysaccharides. Also provided are methods of using polysaccharides for applications such as reducing cholesterol in mammals, inactivating viruses, stabilizing foods, and other uses. Also provided are transgenic algae capable of utilizing fixed carbon sources for energy. Also provided herein are novel nucleic acid sequences from red microalgae.(FR) L'invention porte: sur des compositions de polysaccharides; sur des procédés de culture de microalgues produisant des polysaccharides; sur des procédés d'utilisation desdits polysaccharides dans des applications telles que la réduction du cholestérol chez les mammifères, l'inactivation de virus, la stabilisation d'aliments, etc.; sur des algues transgéniques utilisant des sources de carbone fixé pour produire de l'énergie; et sur de nouvelles séquences d'acides nucléiques de microalgues rouges.
• Synthesis of some galactofuranosyl disaccharides using a galactofuranosyl trichloroacetimidate as donor
  作者：Ambar Kumar Choudhury、Nirmolendu Roy

  DOI：10.1016/s0008-6215(98)00062-7

  日期：1998.3

  2,3,5-Tri-O-benzoyl-6-O-benzyl-beta-D-galactofuranosyl trichloroacetimidate has been prepared for the first time and utilised as glycosyl donor for the synthesis of several disaccharides containing the beta-linked galactofuranoside moiety. (C) 1998 Elsevier Science Ltd. All rights reserved.