2-[[3-(2-Azidoethoxy)phenoxy]methyl]-6-[[4-[tris(4-tert-butylphenyl)methyl]phenoxy]methyl]pyridine | 1426246-21-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-[[3-(2-Azidoethoxy)phenoxy]methyl]-6-[[4-[tris(4-tert-butylphenyl)methyl]phenoxy]methyl]pyridine
• 英文别名: 2-[[3-(2-azidoethoxy)phenoxy]methyl]-6-[[4-[tris(4-tert-butylphenyl)methyl]phenoxy]methyl]pyridine
• CAS: 1426246-21-0
• 化学式: C₅₂H₅₈N₄O₃
• 分子量: 787.058
• InChiKey: JADXRCOYQAHROZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.8
• 重原子数：
  59
• 可旋转键数：
  17
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  54.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-[[3-(2-Azidoethoxy)phenoxy]methyl]-6-[[4-[tris(4-tert-butylphenyl)methyl]phenoxy]methyl]pyridine 、 以 氯仿 、 乙腈 为溶剂， 反应 4.0h， 以87%的产率得到
  参考文献：
  名称：

  A Novel Diketopyrrolopyrrole (DPP)-Based [2]Rotaxane for Highly Selective Optical Sensing of Fluoride

  摘要：

  A novel [2]rotaxane based on an orthogonal H-bonded motif and 3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (DPP) with controlled topicity was successfully constructed, displaying excellent stimulated responses toward anion and solvent polarity. The preorganized host selectively recognized F- with high optical sensitivity and reversibility via enhanced positive cooperativity and noncovalent interaction by evidence of a shorter fluorescence lifetime.

  DOI：

  10.1021/ol400221h
• 作为产物：
  描述：

  3-(2-bromoethoxy)phenol 在 sodium azide 、 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 、 乙腈 为溶剂， 反应 59.0h， 生成 2-[[3-(2-Azidoethoxy)phenoxy]methyl]-6-[[4-[tris(4-tert-butylphenyl)methyl]phenoxy]methyl]pyridine
  参考文献：
  名称：

  A Novel Diketopyrrolopyrrole (DPP)-Based [2]Rotaxane for Highly Selective Optical Sensing of Fluoride

  摘要：

  A novel [2]rotaxane based on an orthogonal H-bonded motif and 3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (DPP) with controlled topicity was successfully constructed, displaying excellent stimulated responses toward anion and solvent polarity. The preorganized host selectively recognized F- with high optical sensitivity and reversibility via enhanced positive cooperativity and noncovalent interaction by evidence of a shorter fluorescence lifetime.

  DOI：

  10.1021/ol400221h

文献信息

• A Novel Diketopyrrolopyrrole (DPP)-Based [2]Rotaxane for Highly Selective Optical Sensing of Fluoride
  作者：Mandapati V. Ramakrishnam Raju、Hong-Cheu Lin

  DOI：10.1021/ol400221h

  日期：2013.3.15

  A novel [2]rotaxane based on an orthogonal H-bonded motif and 3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione (DPP) with controlled topicity was successfully constructed, displaying excellent stimulated responses toward anion and solvent polarity. The preorganized host selectively recognized F- with high optical sensitivity and reversibility via enhanced positive cooperativity and noncovalent interaction by evidence of a shorter fluorescence lifetime.