4-isopropyl-1-methyl cyclohexanecarbaldehyde | 1186290-85-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 4-isopropyl-1-methyl cyclohexanecarbaldehyde
• 英文别名: 1-Methyl-4-(propan-2-YL)cyclohexane-1-carbaldehyde；1-methyl-4-propan-2-ylcyclohexane-1-carbaldehyde
• CAS: 1186290-85-6
• 化学式: C₁₁H₂₀O
• 分子量: 168.279
• InChiKey: DERSKOLBMUCHJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-isopropyl-1-methyl cyclohexanecarbaldehyde 在 sodium chlorite 、 sodium dihydrogenphosphate 、 2-甲基-2-丁烯 作用下， 以 叔丁醇 为溶剂， 反应 0.67h， 生成 1-methyl-4-isopropyl-cyclohexane-carboxylic acid
  参考文献：
  名称：

  PERFUME COMPOSITION

  摘要：

  本发明涉及一种香水组合物，作为水果香型香水的原材料，其具有传统上未知的独特清新、木质、花香、草叶气息，并能够与各种香水协调，提供具有更复杂气味或香气的香水制剂。本发明的香水组合物包括由通式（I）表示的化合物：其中R1和R2分别是具有1至4个碳原子的烃基；而R3是具有2至4个碳原子的烃基。

  公开号：

  US20110071070A1

文献信息

• Perfume composition
  申请人：Kotachi Shinji

  公开号：US08383574B2

  公开（公告）日：2013-02-26

  The present invention relates to a perfume composition as a raw material of fruity perfumes which has a conventionally unknown peculiar fresh, woody, floral, grassy-leafy nuance and is capable of harmonizing with various perfumes to provide perfume preparations having a more sophisticated odor or scent. The perfume composition of the present invention includes a compound represented by the general formula (I): wherein R1 and R2 are each independently a hydrocarbon group having 1 to 4 carbon atoms; and R3 is a hydrocarbon group having 2 to 4 carbon atoms.

  本发明涉及一种香水组合物，作为果香调香料的原材料，具有传统上未知的独特的清新、木质、花香、草叶气息，能够与各种香水协调，提供具有更复杂气味或香气的香水制剂。本发明的香水组合物包括一个由通式（I）表示的化合物：其中R1和R2各自独立地是具有1至4个碳原子的碳氢基团；而R3是具有2至4个碳原子的碳氢基团。
• METHOD FOR SEARCHING FOR MALODOR CONTROL AGENT, MALODOR CONTROL AGENT, AND MALODOR CONTROL METHOD
  申请人：Kao Corporation

  公开号：EP2612923A1

  公开（公告）日：2013-07-10

  Provided are a method for searching for a malodor inhibitor by using the response of an olfactory receptor as an indicator; a method for inhibiting malodor based on the antagonism of olfactory receptors; and a malodor inhibitor. Disclosed are a method for searching for a malodor inhibitor, the method including: adding a test substance and a malodor-causing substance to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1, measuring the response of the olfactory receptor to the malodor-causing substance, identifying the test substance that suppresses the response of the olfactory receptor on the basis of the measured response, and selecting the identified test substance as a malodor inhibitor; an antagonist to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1; a method for inhibiting malodor using the antagonist.

  本发明提供了一种通过将嗅觉受体的反应作为指示器来搜索恶臭抑制剂的方法；一种基于嗅觉受体的拮抗作用来抑制恶臭的方法；以及一种恶臭抑制剂。所公开的是一种寻找恶臭抑制剂的方法，该方法包括向选自 OR51E1、OR2W1、OR10A6、OR51I2 和 OR51L1 组成的组中的任一种嗅觉受体添加测试物质和致恶臭物质，测量嗅觉受体对致恶臭物质的响应，根据测量的响应确定抑制嗅觉受体响应的测试物质，以及选择确定的测试物质作为恶臭抑制剂；选自 OR51E1、OR2W1、OR10A6、OR51I2 和 OR51L1 所组成的组的任何一种嗅觉受体的拮抗剂；使用该拮抗剂抑制恶臭的方法。
• Method for searching for malodor control agent, malodor control agent, and malodor control method
  申请人：Kao Corporation

  公开号：EP2806031A2

  公开（公告）日：2014-11-26

  Provided are a method for searching for a malodor inhibitor by using the response of an olfactory receptor as an indicator; a method for inhibiting malodor based on the antagonism of olfactory receptors; and a malodor inhibitor. Disclosed are a method for searching for a malodor inhibitor, the method including: adding a test substance and a malodor-causing substance to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1, measuring the response of the olfactory receptor to the malodor-causing substance, identifying the test substance that suppresses the response of the olfactory receptor on the basis of the measured response, and selecting the identified test substance as a malodor inhibitor; an antagonist to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1; a method for inhibiting malodor using the antagonist.

  本发明提供了一种通过将嗅觉受体的反应作为指示器来搜索恶臭抑制剂的方法；一种基于嗅觉受体的拮抗作用来抑制恶臭的方法；以及一种恶臭抑制剂。所公开的是一种寻找恶臭抑制剂的方法，该方法包括向选自 OR51E1、OR2W1、OR10A6、OR51I2 和 OR51L1 组成的组中的任一种嗅觉受体添加测试物质和致恶臭物质，测量嗅觉受体对致恶臭物质的响应，根据测量的响应确定抑制嗅觉受体响应的测试物质，以及选择确定的测试物质作为恶臭抑制剂；选自 OR51E1、OR2W1、OR10A6、OR51I2 和 OR51L1 所组成的组的任何一种嗅觉受体的拮抗剂；使用该拮抗剂抑制恶臭的方法。
• Method for searching for malodor control agent
  申请人：Kao Corporation

  公开号：EP2806031B1

  公开（公告）日：2016-11-02
• Method for Searching for Malodor Control Agent, Malodor Control Agent, and Malodor Control Method
  申请人：Kato Aya

  公开号：US20130216492A1

  公开（公告）日：2013-08-22

  Provided are a method for searching for a malodor inhibitor by using the response of an olfactory receptor as an indicator; a method for inhibiting malodor based on the antagonism of olfactory receptors; and a malodor inhibitor. Disclosed are a method for searching for a malodor inhibitor, the method including: adding a test substance and a malodor-causing substance to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1, measuring the response of the olfactory receptor to the malodor-causing substance, identifying the test substance that suppresses the response of the olfactory receptor on the basis of the measured response, and selecting the identified test substance as a malodor inhibitor; an antagonist to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1; a method for inhibiting malodor using the antagonist.