all-trans-farnesyl hexanoate | 51532-28-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: all-trans-farnesyl hexanoate
• 英文别名: (E,E)-farnesyl hexanoate；Farnesyl hexanoate, (E,E)-；[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl] hexanoate
• CAS: 51532-28-6
• 化学式: C₂₁H₃₆O₂
• 分子量: 320.516
• InChiKey: RLRVQTPROCYANT-ZMLAXJCCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  23
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  反式,反式-金合欢醇 、 己酸 以 水 为溶剂， 反应 18.0h， 生成 all-trans-farnesyl hexanoate
  参考文献：
  名称：

  Iwai, Mieko; Okumura, Susumu; Tsujisaka, Yoshio, Agricultural and Biological Chemistry, 1980, vol. 44, # 11, p. 2731 - 2732

  摘要：

  DOI：

文献信息

• Set of Geldanamycin Derivatives and Their Preparation Methods
  申请人：Li Zhuorong

  公开号：US20100311694A1

  公开（公告）日：2010-12-09

  A set of geldanamycin derivatives and their preparation methods. Pharmaceutical compositions comprising the said compounds as an active ingredient which are used as antivirus and antitumor agents. The said derivatives are used in the manufacture of heat shock protein 90 (Hsp 90) inhibiting agents which have the utility as antivirus and antitumor agents.

  一组格尔达纳霉素衍生物及其制备方法。包含所述化合物作为活性成分的制药组合物，用作抗病毒和抗肿瘤剂。所述衍生物用于制造抑制热休克蛋白90（Hsp 90）的药剂，具有作为抗病毒和抗肿瘤剂的功效。
• Host Cells and Methods for Producing Isoprenyl Alkanoates
  申请人：Lee Taek Soon

  公开号：US20100180491A1

  公开（公告）日：2010-07-22

  The invention provides for a method of producing an isoprenyl alkanoate in a genetically modified host cell. In one embodiment, the method comprises culturing a genetically modified host cell which expresses an enzyme capable of catalyzing the esterification of an isoprenol and a straight-chain fatty acid, such as an alcohol acetyltransferase (AAT), wax ester synthase/diacylglycerol acyltransferase (WS/DGAT) or lipase, under a suitable condition so that the isoprenyl alkanoate is produced.
• US9200298B2
  申请人：——

  公开号：US9200298B2

  公开（公告）日：2015-12-01
• US9428726B2
  申请人：——

  公开号：US9428726B2

  公开（公告）日：2016-08-30
• [EN] HOST CELLS AND METHODS FOR PRODUCING ISOPRENYL ALKANOATES<br/>[FR] CELLULES HÔTES ET PROCÉDÉS DE PRODUCTION D'ALCANOATES D'ISOPRÉNYLE
  申请人：UNIV CALIFORNIA

  公开号：WO2009006386A2

  公开（公告）日：2009-01-08

  The invention provides for a method of producing an isoprenyl alkanoate in a genetically modified host cell. In one embodiment, the method comprises culturing a genetically modified host cell which expresses an enzyme capable of catalyzing the esterification of an isoprenol and a straight-chain fatty acid, such as an alcohol acetyltransferase (AAT), wax ester synthase/diacylglycerol acyltransferase (WS/DGAT) or lipase, under a suitable condition so that the isoprenyl alkanoate is produced.