(Z)-8,12-dimethyl-5,5-di(phenylthio)trideca-7,11-dien-4-ol | 833480-05-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (Z)-8,12-dimethyl-5,5-di(phenylthio)trideca-7,11-dien-4-ol
• 英文别名: (7Z)-8,12-dimethyl-5,5-bis(phenylsulfanyl)trideca-7,11-dien-4-ol
• CAS: 833480-05-0
• 化学式: C₂₇H₃₆OS₂
• 分子量: 440.714
• InChiKey: CYTZMNMYDROREY-ATJXCDBQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  30
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  70.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (Z)-8,12-dimethyl-5,5-di(phenylthio)trideca-7,11-dien-4-ol 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 反应 0.25h， 生成 (Z)-8,12-dimethyl-5-phenylthiotrideca-7,11-dien-4-one
  参考文献：
  名称：

  Synthesis of alkyl (α-phenylthioalkenyl) ketones containing a (Z)-trisubstituted olefinic fragment

  摘要：

  Warren's method, which has been proposed for the synthesis of alpha-phenylthiodialkyl ketones, appeared to be inefficient for the preparation of their alkenyl alkyl analogs. The latter were prepared in good yields by alkenylation of alkyl phenylthiomethyl ketones with alkenyl bromides.

  DOI：

  10.1023/b:rucb.0000035654.60768.fb
• 作为产物：
  描述：

  双(苯硫基)甲烷 在 正丁基锂 、 四甲基乙二胺 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 1.0h， 生成 (Z)-8,12-dimethyl-5,5-di(phenylthio)trideca-7,11-dien-4-ol
  参考文献：
  名称：

  Synthesis of alkyl (α-phenylthioalkenyl) ketones containing a (Z)-trisubstituted olefinic fragment

  摘要：

  Warren's method, which has been proposed for the synthesis of alpha-phenylthiodialkyl ketones, appeared to be inefficient for the preparation of their alkenyl alkyl analogs. The latter were prepared in good yields by alkenylation of alkyl phenylthiomethyl ketones with alkenyl bromides.

  DOI：

  10.1023/b:rucb.0000035654.60768.fb

文献信息

• Synthesis of alkyl (α-phenylthioalkenyl) ketones containing a (Z)-trisubstituted olefinic fragment
  作者：N. Ya. Grigorieva、P. G. Tsiklauri

  DOI：10.1023/b:rucb.0000035654.60768.fb

  日期：2004.3

  Warren's method, which has been proposed for the synthesis of alpha-phenylthiodialkyl ketones, appeared to be inefficient for the preparation of their alkenyl alkyl analogs. The latter were prepared in good yields by alkenylation of alkyl phenylthiomethyl ketones with alkenyl bromides.