17,19-Dinoratis-15-ene-4,13,14-tricarboxylic acid, 16-(1-methylethyl)-, (4alpha,8alpha,12alpha,13R,14S)- | 125-66-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 17,19-Dinoratis-15-ene-4,13,14-tricarboxylic acid, 16-(1-methylethyl)-, (4alpha,8alpha,12alpha,13R,14S)-
• 英文别名: 5,9-dimethyl-16-propan-2-yltetracyclo[10.2.2.01,10.04,9]hexadec-15-ene-5,13,14-tricarboxylic acid
• CAS: 125-66-6
• 化学式: C₂₄H₃₄O₆
• 分子量: 418.53
• InChiKey: PXYRCOIAFZBLBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  17,19-Dinoratis-15-ene-4,13,14-tricarboxylic acid, 16-(1-methylethyl)-, (4alpha,8alpha,12alpha,13R,14S)- 在 氯化亚砜 作用下， 生成
  参考文献：
  名称：

  松香衍生物抗真菌活性的定量构效关系

  摘要：

  为了开发具有良好抗真菌活性的新型松香基木材防腐剂，合成了24种松香衍生物，并用Trametes versicolor和Gloeophyllum trabeum进行了生物测定，并对它们的定量构效关系（QSAR）进行了分析。使用Ampac公司9.2.1和Codessa甲QSAR分析2.7.16软件建立抗真菌比两个QSAR模型T.云芝和的G.trabeum用的值- [R 2  = 0.9740和0.9692，分别。基于模型，三- ñ设计了-（3-氢松香氧基-2-羟基）丙基-三乙基氯化铵，生物测定测试结果证明了其对预期的两种真菌的抑制作用更好。

  DOI：

  10.1016/j.bmcl.2014.11.034

文献信息

• Rosin-Based Resin and Toner Containing Same
  申请人：Sacripante Guerino G.

  公开号：US20120183896A1

  公开（公告）日：2012-07-19

  Disclosed is a polyester resin comprising the polycondensation product of (a) at least one diacid, acid ester, or diester; and (b) at least one diol; wherein either (i) at least one diacid, acid ester, or diester comprises a rosin diacid, rosin acid ester, or rosin diester; or (ii) at least one diol comprises a rosin diol. Also disclosed is a toner composition comprising particles which comprise the disclosed polyester resin and an optional colorant.
• Phase Change Inks Containing Oligomeric Rosin Esters
  申请人：XEROX CORPORATION

  公开号：US20140137767A1

  公开（公告）日：2014-05-22

  Disclosed is a phase change ink comprising an ink carrier which comprises a crystalline component and an amorphous rosin ester. In specific embodiments, the crystalline component can be a trans-cinnamic diester, a diester of tartaric acid, or a diurethane. In specific embodiments, the ink exhibits a peak melting point of no more than about 150° C., an onset crystallization temperature of no less than about 60° C., a melt viscosity within the temperature range of from about 100° C. to about 130° C. of from about 5 cps to about 22 cps, a peak solidification viscosity at about 50° C. of no less than about 1×10 6 cps, and a hardness at about 25° C. of at least about 70.
• Oligomeric Rosin Esters for Use in Inks
  申请人：XEROX CORPORATION

  公开号：US20140142334A1

  公开（公告）日：2014-05-22

  Disclosed are ester compounds of the formulae wherein R c is alkylene, arylene, arylalkylene, or alkylarylene as further defined herein, R d is alkylene, arylene, arylalkylene, or alkylarylene as further defined herein, and m and n are integers representing the numbers of repeat monomer units. The materials are suitable for use in inks and other applications.
• METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE
  申请人：Design Therapeutics, Inc.

  公开号：US20210238226A1

  公开（公告）日：2021-08-05

  The present disclosure relates to compounds and methods for modulating the expression of dmpk, atxn1, atxn2, atxn3, cacna1a, atxn7, ppp2r2br tbp, htt, jph3r ar, or atn1 and treating diseases and conditions in which dmpk, atxn1, atxn2, atxn3, cacna1a, atxn1, ppp2r2b, tbp, htt, jph3, ar, or atn1 plays an active role. The compound can be a transcription modulator molecule having a first terminus, a second terminus, and oligomeric backbone, wherein: a) the first terminus comprises a DNA-binding moiety capable of noncovalently binding to a nucleotide repeat sequence CAG or CTG; b) the second terminus comprises a protein-binding moiety binding to a regulatory molecule that modulates an expression of a gene comprising the nucleotide repeat sequence CAG or CTG; and c) the oligomeric backbone comprising a linker between the first terminus and the second terminus.
• US8431303B2
  申请人：——

  公开号：US8431303B2

  公开（公告）日：2013-04-30