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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-methyl-5-[(3S)-1-[(2-methylpyrazol-3-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C18H21F3N6
    2-methyl-5-[(3S)-1-[(2-methylpyrazol-3-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— cyclohexyl-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H25F3N4O
    cyclohexyl-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [4-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone —— C20H23F3N6O
    [4-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone
    —— (5-Tert-butyl-3-methylfuran-2-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C23H27F3N4O2
    (5-Tert-butyl-3-methylfuran-2-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 4-Imidazol-1-yl-1-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]butan-1-one —— C20H23F3N6O
    4-Imidazol-1-yl-1-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]butan-1-one
    —— 2-methyl-5-[(3R)-1-(pyridin-2-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H20F3N5
    2-methyl-5-[(3R)-1-(pyridin-2-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4R)-4-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one —— C21H26F3N5O2
    (4R)-4-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one
    —— 5-[(3S)-1-[(6-methoxy-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H23F3N4O3
    5-[(3S)-1-[(6-methoxy-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (2R)-2-(1,3-benzodioxol-5-yloxy)-1-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C23H23F3N4O4
    (2R)-2-(1,3-benzodioxol-5-yloxy)-1-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— 2-(benzotriazol-2-yl)-1-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C21H20F3N7O
    2-(benzotriazol-2-yl)-1-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— [(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-thiophen-2-ylmethanone —— C18H17F3N4OS
    [(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-thiophen-2-ylmethanone
    —— [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(furan-2-yl)methanone —— C21H23F3N4O2
    [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(furan-2-yl)methanone
    —— [5-(furan-2-yl)-1,2-oxazol-3-yl]-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C21H18F3N5O3
    [5-(furan-2-yl)-1,2-oxazol-3-yl]-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propyl-1H-pyrazol-3-yl)methanone —— C20H23F3N6O
    [4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propyl-1H-pyrazol-3-yl)methanone
    —— 5-[(3S)-1-(furan-2-ylmethyl)piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C18H19F3N4O
    5-[(3S)-1-(furan-2-ylmethyl)piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— cyclohexyl-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H25F3N4O
    cyclohexyl-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 3-(5-methylthiophen-2-yl)-1-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C21H23F3N4OS
    3-(5-methylthiophen-2-yl)-1-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (6-fluoro-1H-benzimidazol-2-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C21H18F4N6O
    (6-fluoro-1H-benzimidazol-2-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (2R)-2-[3-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-oxopropyl]cyclohexan-1-one —— C22H27F3N4O2
    (2R)-2-[3-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-oxopropyl]cyclohexan-1-one
    —— 2-methyl-5-[(3S)-1-(pyridin-2-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H20F3N5
    2-methyl-5-[(3S)-1-(pyridin-2-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-Tert-butyl-5-[1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H27F3N6O
    2-Tert-butyl-5-[1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4-Methyl-1,3-thiazol-5-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H18F3N5OS
    (4-Methyl-1,3-thiazol-5-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 5-[1-[(6-Methoxy-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H23F3N4O3
    5-[1-[(6-Methoxy-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-(benzotriazol-2-yl)-1-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C21H20F3N7O
    2-(benzotriazol-2-yl)-1-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— 3-(5-methylthiophen-2-yl)-1-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C21H23F3N4OS
    3-(5-methylthiophen-2-yl)-1-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— 2-Imidazol-1-yl-1-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C18H19F3N6O
    2-Imidazol-1-yl-1-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone —— C21H27F3N4O2
    [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone
    —— [(3R)-1,1-dioxothiolan-3-yl]-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H21F3N4O3S
    [(3R)-1,1-dioxothiolan-3-yl]-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 1-[4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-phenylpropan-1-one —— C22H23F3N4O
    1-[4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-phenylpropan-1-one
    —— 5-[(3R)-1-[(6-methoxy-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H23F3N4O3
    5-[(3R)-1-[(6-methoxy-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 3-(5-Methyltetrazol-1-yl)-1-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C18H21F3N8O
    3-(5-Methyltetrazol-1-yl)-1-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2S)-2-[3-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-oxopropyl]cyclohexan-1-one —— C22H27F3N4O2
    (2S)-2-[3-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-oxopropyl]cyclohexan-1-one
    —— [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1H-indazol-3-yl)methanone —— C21H23F3N6O
    [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1H-indazol-3-yl)methanone
    —— 3,4,5-trimethoxy-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]benzamide —— C23H23N5O4
    3,4,5-trimethoxy-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]benzamide
    —— [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(1,2-thiazol-4-yl)methanone —— C20H22F3N5OS
    [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(1,2-thiazol-4-yl)methanone
    —— [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(furan-2-yl)methanone —— C21H23F3N4O2
    [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(furan-2-yl)methanone
    —— [4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1H-pyrazol-3-yl)methanone —— C20H23F3N6O
    [4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1H-pyrazol-3-yl)methanone
    —— 2-methyl-5-[(3R)-1-[(2-methylpyrazol-3-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C18H21F3N6
    2-methyl-5-[(3R)-1-[(2-methylpyrazol-3-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 1-[4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-4-pyridin-4-ylbutan-1-one —— C22H24F3N5O
    1-[4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-4-pyridin-4-ylbutan-1-one
    —— 2-Methyl-6-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyridazin-3-one —— C19H19F3N6O2
    2-Methyl-6-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyridazin-3-one
    —— [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-thiophen-2-ylmethanone —— C18H17F3N4OS
    [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-thiophen-2-ylmethanone
    —— [5-(furan-2-yl)-1H-pyrazol-3-yl]-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C21H19F3N6O2
    [5-(furan-2-yl)-1H-pyrazol-3-yl]-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (5-Cyclopropyl-2-methylfuran-3-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C22H23F3N4O2
    (5-Cyclopropyl-2-methylfuran-3-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 2-Benzofuran-1-yl-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C22H19F3N4O2
    2-Benzofuran-1-yl-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 3-(4-acetyl-3,5-dimethylpyrazol-1-yl)-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]propanamide —— C23H25N7O2
    3-(4-acetyl-3,5-dimethylpyrazol-1-yl)-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]propanamide
    —— 2-Methyl-5-[1-[(6-methyl-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H23F3N4O2
    2-Methyl-5-[1-[(6-methyl-1,3-benzodioxol-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 3-(3-methylpyrazol-1-yl)-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]propanamide —— C20H21N7O
    3-(3-methylpyrazol-1-yl)-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]propanamide
    —— [5-(furan-2-yl)-1,2-oxazol-3-yl]-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C21H18F3N5O3
    [5-(furan-2-yl)-1,2-oxazol-3-yl]-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 2-acetamido-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]-1,3-thiazole-4-carboxamide —— C19H17N7O2S
    2-acetamido-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]-1,3-thiazole-4-carboxamide
    —— [4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propylfuran-2-yl)methanone —— C21H23F3N4O2
    [4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propylfuran-2-yl)methanone