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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2,5-dimethyl-N-(pyridin-4-ylmethyl)-3-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-amine —— C18H17N5S
    2,5-dimethyl-N-(pyridin-4-ylmethyl)-3-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-amine
    —— [(1S,3S)-3-methoxycyclohexyl]-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C21H31F3N4O2
    [(1S,3S)-3-methoxycyclohexyl]-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[(1S,3S)-3-methoxycyclohexyl]methanone —— C22H33F3N4O2
    [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[(1S,3S)-3-methoxycyclohexyl]methanone
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone
    —— [(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[(1R,3S)-3-methoxycyclohexyl]methanone —— C22H33F3N4O2
    [(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[(1R,3S)-3-methoxycyclohexyl]methanone
    —— (2S)-2-(1,3-benzodioxol-5-yloxy)-1-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C23H23F3N4O4
    (2S)-2-(1,3-benzodioxol-5-yloxy)-1-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone —— C21H32F2N4O
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone
    —— 2-(4-fluorophenyl)sulfonyl-1-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C20H18F4N4O3S
    2-(4-fluorophenyl)sulfonyl-1-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— [(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone —— C18H26F2N4O
    [(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone —— C21H32F2N4O
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone
    —— [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone —— C21H27F3N4O2
    [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone
    —— (2S)-2-(1,3-benzodioxol-5-yloxy)-1-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C23H23F3N4O4
    (2S)-2-(1,3-benzodioxol-5-yloxy)-1-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone
    —— [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(furan-2-yl)methanone —— C21H23F3N4O2
    [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(furan-2-yl)methanone
    —— 2-[6-(3,5-dimethylpyrazol-1-yl)pyridazin-3-yl]oxy-1-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C23H23F3N8O2
    2-[6-(3,5-dimethylpyrazol-1-yl)pyridazin-3-yl]oxy-1-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone —— C22H23F3N4OS
    [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone
    —— [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2S)-oxolan-2-yl]methanone —— C21H27F3N4O2
    [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2S)-oxolan-2-yl]methanone
    —— [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-cyclopentylmethanone —— C22H29F3N4O
    [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-cyclopentylmethanone
    —— [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-cyclopentylmethanone —— C22H29F3N4O
    [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-cyclopentylmethanone
    —— [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-thiophen-2-ylmethanone —— C21H23F3N4OS
    [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-thiophen-2-ylmethanone
    —— [(3R)-1,1-dioxothiolan-3-yl]-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H21F3N4O3S
    [(3R)-1,1-dioxothiolan-3-yl]-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [4-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone —— C21H27F3N4O2
    [4-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone —— C21H32F2N4O
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone
    —— [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyrazin-2-ylmethanone —— C21H23F3N6O
    [(3S)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyrazin-2-ylmethanone
    —— [(1R,2R)-2-methylcyclopropyl]-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H29F3N4O
    [(1R,2R)-2-methylcyclopropyl]-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2S)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2S)-2-methylcyclopropyl]methanone
    —— [4-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2S)-oxolan-2-yl]methanone —— C21H27F3N4O2
    [4-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2S)-oxolan-2-yl]methanone
    —— [(1R,3S)-3-methoxycyclohexyl]-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C21H31F3N4O2
    [(1R,3S)-3-methoxycyclohexyl]-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone
    —— 1-[4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-methoxypropan-1-one —— C20H27F3N4O2
    1-[4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-methoxypropan-1-one
    —— [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyrazin-2-ylmethanone —— C21H23F3N6O
    [(3R)-3-[2-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyrazin-2-ylmethanone
    —— [4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone —— C20H22F3N5O2
    [4-[2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
    —— [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C21H24F3N5O2
    [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— 1-[4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2,2-dimethylpropan-1-one —— C21H29F3N4O
    1-[4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2,2-dimethylpropan-1-one
    —— 5-[(3S)-1-[[2-(2-methoxyethyl)pyrimidin-5-yl]methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H25F3N6O
    5-[(3S)-1-[[2-(2-methoxyethyl)pyrimidin-5-yl]methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (2R)-2-(1,3-benzodioxol-5-yloxy)-1-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C23H23F3N4O4
    (2R)-2-(1,3-benzodioxol-5-yloxy)-1-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— 1-adamantyl-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C24H29F3N4O
    1-adamantyl-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(2,4-dimethyl-1,3-oxazol-5-yl)methanone —— C22H26F3N5O2
    [4-[2-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(2,4-dimethyl-1,3-oxazol-5-yl)methanone
    —— 2-ethyl-1-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]butan-1-one —— C19H25F3N4O
    2-ethyl-1-[(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]butan-1-one
    —— (4S)-1-cyclopropyl-4-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyrrolidin-2-one —— C21H24F3N5O2
    (4S)-1-cyclopropyl-4-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyrrolidin-2-one
    —— [(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone —— C22H23F3N4OS
    [(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone
    —— 5-[(3R)-1-[[2-(2-methoxyethyl)pyrimidin-5-yl]methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H25F3N6O
    5-[(3R)-1-[[2-(2-methoxyethyl)pyrimidin-5-yl]methyl]piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4R)-1-cyclopropyl-4-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyrrolidin-2-one —— C21H24F3N5O2
    (4R)-1-cyclopropyl-4-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyrrolidin-2-one
    —— [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)methanone —— C21H22F3N5O2
    [(3R)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)methanone
    —— 2-Tert-butyl-5-[1-(pyridin-3-ylmethyl)piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H26F3N5
    2-Tert-butyl-5-[1-(pyridin-3-ylmethyl)piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5,7-dimethyl-N-[2-(5-oxo-4-thiophen-2-yltetrazol-1-yl)ethyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C16H16N8O2S
    5,7-dimethyl-N-[2-(5-oxo-4-thiophen-2-yltetrazol-1-yl)ethyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— (5-Tert-butyl-2-methylpyrazol-3-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C22H27F3N6O
    (5-Tert-butyl-2-methylpyrazol-3-yl)-[4-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 2-ethyl-1-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]butan-1-one —— C19H25F3N4O
    2-ethyl-1-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]butan-1-one
    —— 5-[(3R)-1-(furan-2-ylmethyl)piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C18H19F3N4O
    5-[(3R)-1-(furan-2-ylmethyl)piperidin-3-yl]-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(3S)-1,1-dioxothiolan-3-yl]-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H21F3N4O3S
    [(3S)-1,1-dioxothiolan-3-yl]-[(3S)-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone