Stecholide D | 138629-86-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Stecholide D
• CAS: 138629-86-4
• 化学式: C₂₈H₃₈O₁₁
• 分子量: 550.603
• InChiKey: IAWGDWSLCKHWBJ-FBXLYZAMSA-N

物化性质

• 沸点：
  636.3±55.0 °C(Predicted)
• 密度：
  1.33±0.1 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  Stecholide D 、 丁酰氯 在 吡啶 作用下， 以 乙醚 为溶剂， 反应 3.0h， 生成 Stecholide D butyrate
  参考文献：
  名称：

  Diterpenoids from the gorgonian Solenopodium stechei

  摘要：

  Twenty-five new diterpenoids with representatives from three skeletal classes, briareins, eunicellins, and cembranes, have been isolated from a Pacific gorgonian, Solenopodium stechei. The structural diversity of the diterpenoids isolated indicates significant biosynthetic versatility for this gorgonian. Stecholides 1-20 are diterpene lactones of the briarein family distinguished by the presence of an alpha,beta-epoxide group in the lactone ring. These structures were deduced by spectroscopic analyses. The structure of solenopodin D, 24, a eunicellin-type diterpenoid, was established by X-ray analysis while the structures of three other solenopodins, 20-23, were confirmed by spectral analyses and comparison to data for 24. Solenopodins A-D are the only eunicellin-type diterpenoids isolated to date which do not have an ether bridge across the 10-membered carbocyclic ring. Only one cembranoid, 25, was isolated. Diterpenoids 1, 3, and 20 show cytotoxicity to murine leukemia cells (P388).

  DOI：

  10.1021/jo00030a031