| 546124-64-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 546124-64-5
• 化学式: C₄₂H₅₇Cl₃F₃N₃O₂₅
• 分子量: 1167.27
• InChiKey: MXZBGDOGCQCEJX-FOCCFEELSA-N

反应信息

• 作为反应物：
  描述：

  在 甲醇 、 sodium hydroxide 、 水 、 sodium methylate 、 溶剂黄146 、 锌 作用下， 生成
  参考文献：
  名称：

  Synthesis of N-acetyllactosamine-terminated oligosaccharides — fragments of glycoprotein O-chains

  摘要：

  The pentasaccharide Galbeta1-4GlcNAcbeta1-6(Galbeta1-4GlcNAcbeta1-3)GalNAcalphaOR, its partial trisaccharides Galbeta1-4GlcNAcbeta1-3GalNAcalphaOR and Galbeta1-4GlcNAcbeta1-6GalNAcalphaOR and the tetrasaccharide Galbeta1-4GlcNAcbeta1-6(Galbeta1-3)GalNAcalphaOR were synthesised as spacered derivatives (R = CH2CH2CH2NH2) using a Troc-protected lactosamine glycosyl donor at the key stage.

  DOI：

  10.1070/mc2002v012n05abeh001653
• 作为产物：
  描述：

  Acetic acid (2S,3R,4R,5R,6R)-3-acetylamino-5-hydroxy-6-hydroxymethyl-2-[3-(2,2,2-trifluoro-acetylamino)-propoxy]-tetrahydro-pyran-4-yl ester 、 Acetic acid (2R,3S,4R,5R,6R)-2-acetoxymethyl-6-bromo-3-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-5-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-4-yl ester 在 silver trifluoromethanesulfonate 、 1,1,3,3-四甲基脲 作用下， 以78%的产率得到
  参考文献：
  名称：

  Synthesis of N-acetyllactosamine-terminated oligosaccharides — fragments of glycoprotein O-chains

  摘要：

  The pentasaccharide Galbeta1-4GlcNAcbeta1-6(Galbeta1-4GlcNAcbeta1-3)GalNAcalphaOR, its partial trisaccharides Galbeta1-4GlcNAcbeta1-3GalNAcalphaOR and Galbeta1-4GlcNAcbeta1-6GalNAcalphaOR and the tetrasaccharide Galbeta1-4GlcNAcbeta1-6(Galbeta1-3)GalNAcalphaOR were synthesised as spacered derivatives (R = CH2CH2CH2NH2) using a Troc-protected lactosamine glycosyl donor at the key stage.

  DOI：

  10.1070/mc2002v012n05abeh001653