α-D-Glcp-(1->4)-β-D-Galp-(1->3)-β-D-GalpNAc-(1->4)-α-D-Galp-(1->4)-β-Leg5Ac7Ac | 1350625-74-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-D-Glcp-(1->4)-β-D-Galp-(1->3)-β-D-GalpNAc-(1->4)-α-D-Galp-(1->4)-β-Leg5Ac7Ac
• 英文别名: Glc(a1-4)Gal(b1-3)GalNAc(b1-4)Gal(a1-4)3,9-deoxy-D-gro-b-D-galNon2ulo5NAc7NAc-onic；(2S,4S,5R,6S)-5-acetamido-4-[(2S,3R,4R,5R,6R)-5-[(2S,3R,4R,5R,6R)-3-acetamido-4-[(2R,3R,4R,5R,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[(1R,2R)-1-acetamido-2-hydroxypropyl]-2-hydroxyoxane-2-carboxylic acid
• CAS: 1350625-74-9
• 化学式: C₃₉H₆₅N₃O₂₈
• 分子量: 1023.95
• InChiKey: VFQDPTKTHVQOHN-HQUVXEIYSA-N

反应信息

• 作为反应物：
  描述：

  α-D-Glcp-(1->4)-β-D-Galp-(1->3)-β-D-GalpNAc-(1->4)-α-D-Galp-(1->4)-β-Leg5Ac7Ac 、 乙酸酐 、 碘甲烷 在 水 、 sodium hydroxide 、 三氟乙酸 作用下， 以 二甲基亚砜 、 水 为溶剂， 生成 1,5-di-O-acetyl-1-deuterio-2,3,4,6-tetra-O-methyl-D-glucitol 、 1,3,5-tri-O-acetyl-2-(N-methylacetamido)-2-deoxy-4,6-di-O-methyl-D-galactitol-1-d 、 1,4,5-tri-O-acetyl-1-deuterio-2,3,6-tri-O-methyl-D-galactitol
  参考文献：
  名称：

  Characterization of the lipopolysaccharide O-antigen of Cronobacter turicensis HPB3287 as a polysaccharide containing a 5,7-diacetamido-3,5,7,9-tetradeoxy-d-glycero-d-galacto-non-2-ulosonic acid (legionaminic acid) residue

  摘要：

  Cronobacter turicensis, previously known as Enterobacter sakazakii, is a Gram-negative opportunistic foodborne pathogen that has been reported as a cause of life-threatening neonatal infections. From chemical and physical analyses involving composition analysis, methylation, two-dimensional high-resolution nuclear magnetic resonance, and mass spectrometry methods, the antigenic 0-polysaccharide in the smooth-type lipopolysaccharide of C. turicensis (strain HPB 3287) was determined to be a high molecular mass polymer of a repeating pentasaccharide unit composed of D-galactose, D-glucose, 2-acetamido-2-deoxy-D-galactose, and 5,7-diacetamido-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid (leg-ionaminic acid), in a molar ratio 2:1:1:1, and having the structure:alpha-D-Glcp1down arrow4[-> 3)-beta-D-Galp-(1 -> 3)-beta-D-GalpNAc-(1 -> 4)-alpha-D-Galp-(1 -> 4)-alpha-Leg5Ac7Ac-(2 ->](0). (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2011.09.003