| 1340547-65-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• CAS: 1340547-65-0
• 化学式: C₁₂H₁₂F₂OS
• 分子量: 242.289
• InChiKey: DYODGWNNQWOPFO-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 一水合肼 、 溶剂黄146 作用下， 以 叔丁醇 为溶剂， 反应 5.0h， 以80%的产率得到5-(3,5-difluorophenyl)-3-methyl-1H-pyrazole
  参考文献：
  名称：

  Regioselective synthesis of multisubstituted pyrazoles via cyclocondensation of β-thioalkyl-α,β-unsaturated ketones with hydrazines

  摘要：

  Multisubstituted pyrazoles were efficiently synthesized by cyclocondensation of beta-thioalkyl-alpha,beta-unsaturated ketones with hydrazines under relatively mild conditions. A one-pot synthetic protocol through tandem Liebeskind-Srogl cross-coupling/cyclocondensation using alpha-oxo ketene dithioacetals as the starting materials was also realized for the same purpose. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.08.168