3-isocyanato-2-(3-phenoxyphenoxy)pyridine | 185214-64-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-isocyanato-2-(3-phenoxyphenoxy)pyridine
• CAS: 185214-64-6
• 化学式: C₁₈H₁₂N₂O₃
• 分子量: 304.305
• InChiKey: DTPHUYXIQHYHNV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  60.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-isocyanato-2-(3-phenoxyphenoxy)pyridine 、 偏二甲肼 、 三光气 在 水 、 乙醚 、 氯化钠 、 magnesium sulfate 、 silica gel 、 乙酸乙酯 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 32.0h， 以ethyl acetate as the eluent to yield 2 g of the title compound of Step C的产率得到5-chloro-2,4-dihydro-2-methyl-4-[2-(3-phenoxyphenoxy)-3-pyridinyl]-3H-1,2,4-triazol-3-one
  参考文献：
  名称：

  Heterocyclic dihydrazole compounds and their use for controlling fungal

  摘要：

  本发明涉及公式I及其N-氧化物和农业适用的盐的化合物，其可用作杀菌剂。在公式中，E是选自某些5-至12-成员单环和融合双环芳香杂环环系或根据公开说明定义的可选取代萘环的环系；A是O；S；N；NR.sup.5；或CR.sup.14；G是C或N；当G为C时，A为O、S或NR.sup.5，浮动双键连接到G；当G为N时，A为N或CR.sup.14，浮动双键连接到A；W是O；S；NH；N(C.sub.1-C.sub.6烷基)；或NO(C.sub.1-C.sub.6烷基)；X是OR.sup.1；S(O).sub.mR.sup.1；或卤素；R.sup.1是C.sub.1-C.sub.6烷基；C.sub.1-C.sub.6卤代烷基；C.sub.2-C.sub.6烯基；C.sub.2-C.sub.6卤代烯基；C.sub.2-C.sub.6炔基；C.sub.2-C.sub.6卤代炔基；C.sub.3-C.sub.6环烷基；C.sub.2-C.sub.4烷基羰基；或C.sub.2-C.sub.4烷氧羰基；R.sup.2是H；C.sub.1-C.sub.6烷基；C.sub.1-C.sub.6卤代烷基；C.sub.2-C.sub.6烯基；C.sub.2-C.sub.6卤代烯基；C.sub.2-C.sub.6炔基；C.sub.2-C.sub.6卤代炔基；C.sub.3-C.sub.6环烷基；C.sub.2-C.sub.4烷基羰基；C.sub.2-C.sub.4烷氧羰基；羟基；C.sub.1-C.sub.2烷氧基；或乙酰氧基；R.sup.5是H；C.sub.1-C.sub.6烷基；C.sub.1-C.sub.6卤代烷基；C.sub.2-C.sub.6烯基；C.sub.2-C.sub.6卤代烯基；C.sub.2-C.sub.6炔基；C.sub.2-C.sub.6卤代炔基；C.sub.3-C.sub.6环烷基；C.sub.2-C.sub.4烷基羰基；或C.sub.2-C.sub.4烷氧羰基；Y、Z、R.sup.14和m如公开说明所定义。还公开了含有公式I化合物的组合物以及一种控制由真菌植物病原体引起的植物病害的方法，该方法涉及施用公式I化合物的有效量。

  公开号：

  US06096895A1

文献信息

• FUNGICIDAL CYCLIC AMIDES
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0825992A1

  公开（公告）日：1998-03-04
• US6096895A
  申请人：——

  公开号：US6096895A

  公开（公告）日：2000-08-01
• [EN] FUNGICIDAL CYCLIC AMIDES<br/>[FR] AMIDES CYCLIQUES FONGIQUES
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：WO1996036633A1

  公开（公告）日：1996-11-21

  (EN) Compounds of Formula (I), and their N-oxides and agriculturally suitable salts, are disclosed which are useful as fungicides. In said formula, E is a ring system selected from certain 5- to 12-membered monocyclic and fused bicyclic aromatic heterocyclic ring systems, or an optionally substituted naphthalene ring as defined in the disclosure; A is O; S; N; NR5; or CR14; G is C or N; provided that when G is C, then A is O, S or NR5 and the floating double bond is attached to G; and when G is N, then A is N or CR14 and the floating double bond is attached to A; W is O; S; NH; N(C1-C6 alkyl); or NO(C1-C6 alkyl); X is OR1; S(O)mR1; or halogen; R1 is C1-C6 alkyl; C1-C6 haloalkyl; C2-C6 alkenyl; C2-C6 haloalkenyl; C2-C6 alkynyl; C2-C6 haloalkynyl; C3-C6 cycloalkyl; C2-C4 alkylcarbonyl; or C2-C4 alkoxycarbonyl; R2 is H; C1-C6 alkyl; C1-C6 haloalkyl; C2-C6 alkenyl; C2-C6 haloalkenyl; C2-C6 alkynyl; C2-C6 haloalkynyl; C3-C6 cycloalkyl; C2-C4 alkylcarbonyl; C2-C4 alkoxycarbonyl; hydroxy; C1-C2 alkoxy; or acetyloxy; R5 is H; C1-C6 alkyl; C1-C6 haloalkyl; C2-C6 alkenyl; C2-C6 haloalkenyl; C2-C6 alkynyl; C2-C6 haloalkynyl; C3-C6 cycloalkyl; C2-C4 alkylcarbonyl; or C2-C4 alkoxycarbonyl; and Y, Z, R14 and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (I) and a method for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound of Formula (I).(FR) La présente invention concerne des composés utiles en tant que fongicides, représentés par la formule (I), ainsi que leurs oxydes d'azote et leurs sels utilisables en agriculture. Dans la formule (I), E est un système cyclique sélectionné parmi certains systèmes cycliques hétérocycliques aromatiques bicycliques condensés et monocyles ayant de 5 à 12 chaînons, ou un noyau naphtalène éventuellement substitué semblable à ceux définis dans le descriptif de l'invention, A est O, S, N, NR5 ou CR14, G est C ou N, pourvu que lorsque G est C, alors A est O, S ou NR5 et la double liaison flottante est attachée à G, et lorsque G est N, alors A est N ou CR14 et la double liaison flottante est attachée à A, W est O, S, NH, N(alkyle C1-C6) ou NO(alkyle C1-C6), X est OR1, S(O)mR1 ou halogène, R1 est alkyle C1-C6, haloalkyle C1-C6, alkényle C2-C6, haloalkényle C2-C6, alkynyle C2-C6, haloalkynyle C2-C6, cycloalkyle C3-C6, alkylcarbonyle C2-C4 ou alkoxycarbonyle C2-C4, R2 est H, alkyle C1-C6, haloalkyle C1-C6, alkényle C2-C6, haloalkényle C2-C6, alkynyle C2-C6, haloalkynyle C2-C6, cycloalkyle C3-C6, alkylcarbonyle C2-C4 ou alkoxycarbonyle C2-C4, hydroxy, alkoxy C1-C2 ou acétyloxy, R5 est H, alkyle C1-C6, haloalkyle C1-C6, alkényle C2-C6, haloalkényle C2-C6, alkynyle C2-C6, haloalkynyle C2-C6, cycloalkyle C3-C6, alkylcarbonyle C2-C4 ou alkoxycarbonyle C2-C4, et Y, Z, R14 et m sont définis dans le descriptif de l'invention. Cette invention concerne également des compositions contenant les composés représentés par la formule (I) ainsi qu'un procédé de lutte contre les maladies des plantes provoquées par des éléments pathogènes fongiques des plantes, ledit procédé consistant à appliquer une quantité efficace d'un composé représenté par la formule (I).
• Heterocyclic dihydrazole compounds and their use for controlling fungal
  申请人：E. I. du Pont de Nemours and Company

  公开号：US06096895A1

  公开（公告）日：2000-08-01

  Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful as fungicides ##STR1## In said formula, E is a ring system selected from certain 5- to 12-membered monocyclic and fused bicyclic aromatic heterocyclic ring systems, or an optionally substituted naphthalene ring as defined in the disclosure; A is O; S; N; NR.sup.5 ; or CR.sup.14 ; G is C or N; provided that when G is C, then A is O, S or NR.sup.5 and the floating double bond is attached to G; and when G is N, then A is N or CR.sup.14 and the floating double bond is attached to A; W is O; S; NH; N(C.sub.1 -C.sub.6 alkyl); or NO(C.sub.1 -C.sub.6 alkyl); X is OR.sup.1 ; S(O).sub.m R.sup.1 ; or halogen; R.sup.1 is C.sub.1 -C.sub.6 alkyl; C.sub.1 -C.sub.6 haloalkyl; C.sub.2 -C.sub.6 alkenyl; C.sub.2 -C.sub.6 haloalkenyl; C.sub.2 -C.sub.6 alkynyl; C.sub.2 -C.sub.6 haloalkynyl; C.sub.3 -C.sub.6 cycloalkyl; C.sub.2 -C.sub.4 alkylcarbonyl; or C.sub.2 -C.sub.4 alkoxycarbonyl; R.sup.2 is H; C.sub.1 -C.sub.6 alkyl; C.sub.1 -C.sub.6 haloalkyl; C.sub.2 -C.sub.6 alkenyl; C.sub.2 -C.sub.6 haloalkenyl; C.sub.2 -C.sub.6 alkynyl; C.sub.2 -C.sub.6 haloalkynyl; C.sub.3 -C.sub.6 cycloalkyl; C.sub.2 -C.sub.4 alkylcarbonyl; C.sub.2 -C.sub.4 alkoxycarbonyl; hydroxy; C.sub.1 -C.sub.2 alkoxy; or acetyloxy; R.sup.5 is H; C.sub.1 -C.sub.6 alkyl; C.sub.1 -C.sub.6 haloalkyl; C.sub.2 -C.sub.6 alkenyl; C.sub.2 -C.sub.6 haloalkenyl; C.sub.2 -C.sub.6 alkynyl; C.sub.2 -C.sub.6 haloalkynyl; C.sub.3 -C.sub.6 cycloalkyl; C.sub.2 -C.sub.4 alkylcarbonyl; or C.sub.2 -C.sub.4 alkoxycarbonyl; and Y, Z, R.sup.14 and m are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling plant diseases caused by fungal plant pathogens which involves applying an effective amount of a compound of Formula I.

  公式I的化合物及其N-氧化物和农业适用的盐被披露，可用作杀菌剂。在上述公式中，E是从某些5-至12-成员单环和融合的双环芳香杂环环系统中选择的环系统，或者是如披露中定义的可选择取代的萘环；A是O；S；N；NR^5；或CR^14；G是C或N；但要求当G为C时，A为O、S或NR^5且浮动双键连接到G；当G为N时，A为N或CR^14且浮动双键连接到A；W是O；S；NH；N(C_1-C_6烷基)；或NO(C_1-C_6烷基)；X是OR^1；S(O)_mR^1；或卤素；R^1是C_1-C_6烷基；C_1-C_6卤代烷基；C_2-C_6烯基；C_2-C_6卤代烯基；C_2-C_6炔基；C_2-C_6卤代炔基；C_3-C_6环烷基；C_2-C_4烷基羰基；或C_2-C_4烷氧羰基；R^2是H；C_1-C_6烷基；C_1-C_6卤代烷基；C_2-C_6烯基；C_2-C_6卤代烯基；C_2-C_6炔基；C_2-C_6卤代炔基；C_3-C_6环烷基；C_2-C_4烷基羰基；C_2-C_4烷氧羰基；羟基；C_1-C_2烷氧基；或乙酰氧基；R^5是H；C_1-C_6烷基；C_1-C_6卤代烷基；C_2-C_6烯基；C_2-C_6卤代烯基；C_2-C_6炔基；C_2-C_6卤代炔基；C_3-C_6环烷基；C_2-C_4烷基羰基；或C_2-C_4烷氧羰基；Y、Z、R^14和m如披露中所定义。还披露了含有公式I化合物的组合物以及一种用于控制由真菌植物病原体引起的植物疾病的方法，该方法涉及施用公式I的化合物的有效量。