tert-butyl-[(7,7-dideuterio-1-bicyclo[4.1.0]heptanyl)oxy]-dimethylsilane | 127375-76-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: tert-butyl-[(7,7-dideuterio-1-bicyclo[4.1.0]heptanyl)oxy]-dimethylsilane
• CAS: 127375-76-2
• 化学式: C₁₃H₂₆OSi
• 分子量: 228.418
• InChiKey: RYRWFMUJGAIFHQ-KBMKNGFXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.34
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  tert-butyl-[(7,7-dideuterio-1-bicyclo[4.1.0]heptanyl)oxy]-dimethylsilane 在 di(rhodium)tetracarbonyl dichloride 作用下， 反应 40.0h， 生成
  参考文献：
  名称：

  铑（I）催化的甲硅烷氧基环丙烷异构化，生成烯醇甲硅烷基醚和烯丙基甲硅烷基醚

  摘要：

  通过使用[Rh（CO）2 Cl] 2作为催化剂，将甲硅烷氧基环丙烷异构化为烯醇甲硅烷基醚和烯丙基甲硅烷基醚。关于产物的新形成的双键的区域化学高度依赖于环丙烷环的取代模式。

  DOI：

  10.1016/s0040-4039(01)93380-5

文献信息

• .beta.-Trichlorostannyl ketones and aldehydes. Preparation and facile amine-induced dehydrostannation leading to .alpha.-methylene ketones and aldehydes
  作者：Hiroyuki Nakahira、Ilhyong Ryu、Masanobu Ikebe、Yoshiaki Oku、Akiya Ogawa、Nobuaki Kambe、Noboru Sonoda、Shinji Murai

  DOI：10.1021/jo00027a008

  日期：1992.1

  Ring-opening reactions of siloxycyclopropanes 1 with SnCl4 take place under mild reaction conditions and site-selectively to give beta-trichlorostannyl ketones and aldehydes 3 in high yields. The beta-trichlorostannyl ketones and aldehydes thus obtained readily undergo base-induced dehydrotrichlorostannation at room temperature to give the corresponding alpha-methylene ketones and aldehydes 4. The reactions are quite general for amines, such as pyridine, triethylamine, N,N,N',N'-tetramethylethylenediamine (TMEDA), and 1,4-diazabicyclo[2.2.2]octane (DABCO), and the yields are good to high. One-pot conversion from siloxycyclopropanes 1 to alpha-methylene ketones or aldehydes 4 by consecutive treatment of 1 with SnCl4 and TMEDA is also successful. The H-1 NMR, C-13 NMR, Sn-119 NMR, and IR spectral properties of beta-stannyl ketones and aldehydes are also reported.
• Room temperature isomerization of siloxycyclopropanes to silyl ethers of 2-methylenealkanols catalyzed by Zeise's dimer
  作者：Kiyoshi Ikura、Ilhyong Ryu、Nobuaki Kambe、Noboru Sonoda

  DOI：10.1021/ja00030a080

  日期：1992.2