pusilatin E | 183986-63-2

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: pusilatin E
• 英文别名: 17-(16,24-Dihydroxy-5-methoxy-14-oxapentacyclo[20.2.2.210,13.115,19.02,7]nonacosa-1(24),2(7),3,5,10(29),11,13(28),15(27),16,18,22,25-dodecaen-17-yl)-5-methoxy-14-oxapentacyclo[20.2.2.210,13.115,19.02,7]nonacosa-1(24),2(7),3,5,10(29),11,13(28),15(27),16,18,22,25-dodecaene-16,24-diol
• CAS: 183986-63-2
• 化学式: C₅₈H₅₀O₈
• 分子量: 875.03
• InChiKey: VPTMTVAGSCSUCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.4
• 重原子数：
  66
• 可旋转键数：
  3
• 环数：
  16.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  118
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  pusilatin E 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以16.4 mg的产率得到pusilatin B
  参考文献：
  名称：

  Isolation, Structure Elucidation, and Chemical Derivatization of a New Cyclic Bisbibenzyl Dimer, Pusilatin E, from the Liverwort Riccardia multifida subsp. decrescens

  摘要：

  A new cyclic bisbibenzyl dimer (1) has been isolated from the MeOH extract of the liverwort Riccardia multifida subsp. decrescens, together with two previously known bisbibenzyls [riccardin A (2) and marchantin I (3)] and a norneolignan [egonol 2-methylbutanoate (4)]. Extensive H-1- and C-13-NMR spectral measurements and chemical derivatization allowed the structure of dimeric riccardin A to be defined; it has been named pusilatin E (1).

  DOI：

  10.1021/np9605697
• 作为产物：
  描述：

  Riccardin A 在 manganese triacetate 作用下， 以 乙醇 为溶剂， 反应 1.0h， 以38%的产率得到pusilatin E
  参考文献：
  名称：

  Isolation, Structure Elucidation, and Chemical Derivatization of a New Cyclic Bisbibenzyl Dimer, Pusilatin E, from the Liverwort Riccardia multifida subsp. decrescens

  摘要：

  A new cyclic bisbibenzyl dimer (1) has been isolated from the MeOH extract of the liverwort Riccardia multifida subsp. decrescens, together with two previously known bisbibenzyls [riccardin A (2) and marchantin I (3)] and a norneolignan [egonol 2-methylbutanoate (4)]. Extensive H-1- and C-13-NMR spectral measurements and chemical derivatization allowed the structure of dimeric riccardin A to be defined; it has been named pusilatin E (1).

  DOI：

  10.1021/np9605697

文献信息

• Isolation, Structure Elucidation, and Chemical Derivatization of a New Cyclic Bisbibenzyl Dimer, Pusilatin E, from the Liverwort <i>Riccardia multifida</i> subsp. <i>decrescens</i>
  作者：Tatsuhiko Yoshida、Masao Toyota、Yoshinori Asakawa

  DOI：10.1021/np9605697

  日期：1997.2.1

  A new cyclic bisbibenzyl dimer (1) has been isolated from the MeOH extract of the liverwort Riccardia multifida subsp. decrescens, together with two previously known bisbibenzyls [riccardin A (2) and marchantin I (3)] and a norneolignan [egonol 2-methylbutanoate (4)]. Extensive H-1- and C-13-NMR spectral measurements and chemical derivatization allowed the structure of dimeric riccardin A to be defined; it has been named pusilatin E (1).