(R)-1-((4R,5R)-5-allyl-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol | 1261239-00-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (R)-1-((4R,5R)-5-allyl-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol
• 英文别名: (1R)-1-[(4R,5R)-2,2-dimethyl-5-prop-2-enyl-1,3-dioxolan-4-yl]ethanol
• CAS: 1261239-00-2
• 化学式: C₁₀H₁₈O₃
• 分子量: 186.251
• InChiKey: FHTZPUYCSXHXTD-IWSPIJDZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (R)-1-((4R,5R)-5-allyl-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol 在 对甲苯磺酸 作用下， 以 甲醇 为溶剂， 以75%的产率得到(2R,3R,4R)-hept-6-ene-2,3,4-triol
  参考文献：
  名称：

  An efficient synthesis of synargentolide A from d-mannitol

  摘要：

  An efficient synthesis of synargentolide A is described by using D-mannitol and D-malic acid The key features of the synthetic strategy include Wittig olefination ring closing-metathesis reaction and cross-metathesis reaction for the formation of synargentolide A (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tetasy.2010.10.001
• 作为产物：
  描述：

  在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 以0.42 g的产率得到(R)-1-((4R,5R)-5-allyl-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol
  参考文献：
  名称：

  An efficient synthesis of synargentolide A from d-mannitol

  摘要：

  An efficient synthesis of synargentolide A is described by using D-mannitol and D-malic acid The key features of the synthetic strategy include Wittig olefination ring closing-metathesis reaction and cross-metathesis reaction for the formation of synargentolide A (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tetasy.2010.10.001

文献信息

• An efficient synthesis of synargentolide A from d-mannitol
  作者：Ahmed Kamal、Moku Balakrishna、Papagari Venkat Reddy、Shaikh Faazil

  DOI：10.1016/j.tetasy.2010.10.001

  日期：2010.10

  An efficient synthesis of synargentolide A is described by using D-mannitol and D-malic acid The key features of the synthetic strategy include Wittig olefination ring closing-metathesis reaction and cross-metathesis reaction for the formation of synargentolide A (C) 2010 Elsevier Ltd All rights reserved