Stach-15-en-7β,12β,17-triol-triacetat | 52088-78-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Stach-15-en-7β,12β,17-triol-triacetat
• 英文别名: [(1S,2S,4R,9R,10S,12R,13S)-2,12-diacetyloxy-5,5,9-trimethyl-13-tetracyclo[11.2.1.01,10.04,9]hexadec-14-enyl]methyl acetate
• CAS: 52088-78-5
• 化学式: C₂₆H₃₈O₆
• 分子量: 446.584
• InChiKey: BTGMOLZVNPSKGG-LORLSVMBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  32
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  Stach-15-en-7β,12β,17-triol-triacetat 在 氢氧化钾 作用下， 生成 Stach-15-en-7β,12β,17-triol-7β-acetat
  参考文献：
  名称：

  von Carstenn-Lichterfelde,C. et al., Australian Journal of Chemistry, 1974, vol. 27, p. 517 - 529

  摘要：

  DOI：

文献信息

• Four new diterpenes from Sideritis serrata
  作者：Teresa G. de Quesada、Benjamín Rodríguez、Serafín Valverde

  DOI：10.1016/0031-9422(75)85120-x

  日期：1975.2

  Abstract Four new diterpenes have been isolated from Sideritis serata : lagascol ( 4 , ent -8,5- friedo pimar-5-ene-15 S ,16-diol), tobarrol ( 8 , ent -15-beyerene-12α,17-diol), benuol ( 12 , ent -15-beyerene-7α,17-diol) and serradiol ( 18 , ent -16 R -atis-13-ene-16,17-diol). The previously known diterpenes lagascatriol ( 1 , ent -8,5- friedo pimar-5-ene-11β,15 S ,16-triol), jativatriol ( 2 , ent

  摘要 从锯齿石斛中分离得到四种新的二萜：lagascol ( 4 , ent -8,5- Friedo pimar-5-ene-15 S ,16-diol), tobarrol ( 8 , ent -15-beyerene-12α,17- diol)、benuol​​ (12, ent -15-beyerene-7α,17-diol) 和serradiol (18, ent -16 R -atis-13-ene-16,17-diol)。先前已知的二萜lagascatriol (1, ent -8,5-friedo pimar-5-ene-11β,15 S,16-triol), jativatriol (2, ent -15-beyerene-1β,12α,17-triol), conchitriol ( 3 , ent -15-beyerene-7α,12α,17-triol) 和 sideritol
• Biotransformation of <i>ent</i>-Atisenes and <i>ent</i>-Beyerenes by <i>Rhizopus nigricans</i> and <i>Fusarium moniliforme </i>Cultures
  作者：Andrés García-Granados、Andrés Parra、José María Arias

  DOI：10.1021/np960426k

  日期：1997.2.1

  Microbial transformations of ent-atisene and ent-beyerene compounds were carried out using cultures of R. nigricans and F. moniliforme. Rhizopus nigricans metabolized all of the substrates, at higher yields than F. moniliforme, to give an ent-3 beta hydroxylation (60-65% for ent-atisenes and 80-85% for ent-beyerenes). Moreover, the double bond of the ent-beyerene skeleton was epoxidized by both fungi at lower yields (3-6%). Fusarium moniliforme produced a number of additional minor products by hydroxylation at other positions.