(Z)-3-[2-azido-4-[(4-methoxyphenyl)methoxy]phenyl]prop-2-enoic acid | 1037305-17-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (Z)-3-[2-azido-4-[(4-methoxyphenyl)methoxy]phenyl]prop-2-enoic acid
• CAS: 1037305-17-1
• 化学式: C₁₇H₁₅N₃O₄
• 分子量: 325.324
• InChiKey: GFXHDAKOQHUACH-UITAMQMPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  70.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N-羟基丁二酰亚胺 、 (Z)-3-[2-azido-4-[(4-methoxyphenyl)methoxy]phenyl]prop-2-enoic acid 在 N,N'-二环己基碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of photoaffinity probe based on the leaf-opening factor from genus Albizzia

  摘要：

  The circadian rhythmic leaf-movements in legumes, called nyctinasty, are regulated by a pair of leaf-closing and -opening factors. Recent fluorescence studies revealed that cis-p-coumaroylagmatine (1), the leaf-opening factor from genus Albizzia, specifically bound to motor cells in a joint of leaf and stem. in order to identify the receptor protein, which is expected to be involved in the plasma membrane of the cell, we designed and synthesized a photoaffinity probe (2), containing a photoreactive azide group on the aromatic ring and FLAG segment as a peptide antigen for immunoprecipitation. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.002
• 作为产物：
  描述：

  在 sodium chlorite 、 2-甲基-2-丁烯 、 camphor-10-sulfonic acid 作用下， 生成 (Z)-3-[2-azido-4-[(4-methoxyphenyl)methoxy]phenyl]prop-2-enoic acid
  参考文献：
  名称：

  Synthesis of photoaffinity probe based on the leaf-opening factor from genus Albizzia

  摘要：

  The circadian rhythmic leaf-movements in legumes, called nyctinasty, are regulated by a pair of leaf-closing and -opening factors. Recent fluorescence studies revealed that cis-p-coumaroylagmatine (1), the leaf-opening factor from genus Albizzia, specifically bound to motor cells in a joint of leaf and stem. in order to identify the receptor protein, which is expected to be involved in the plasma membrane of the cell, we designed and synthesized a photoaffinity probe (2), containing a photoreactive azide group on the aromatic ring and FLAG segment as a peptide antigen for immunoprecipitation. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.002